Comparison of surveillance-based metrics for the assessment and monitoring of disease detection: simulation study about type 2 diabetes

Details

• Alternative Title:
  BMC Med Res Methodol
• Personal Author:
  Brinks, Ralph ; Hoyer, Annika ; Rolka, Deborah B. ; Kuss, Oliver ; Gregg, Edward W.
• Description:
  Background ; Screening and detection of cases are a common public health priority for treatable chronic conditions with long subclinical periods. However, the validity of commonly-used metrics from surveillance systems for rates of detection (or case-finding) have not been evaluated. ; Methods ; Using data from a Danish diabetes register and a recently developed illness-death model of chronic diseases with subclinical conditions, we simulate two scenarios of different performance of case-finding. We report different epidemiological indices to assess case-finding in both scenarios and compare the validity of the results. ; Results ; The commonly used ratio of detected cases over total cases may lead to misleading conclusions. Instead, the ratio of undetected cases over persons without a diagnosis is a more valid index to distinguish the quality of case-finding. However, incidence-based measures are preferable to prevalence based indicators. ; Conclusion ; Prevalence-based indices for assessing case-finding should be interpreted with caution. If possible, incidence-based indices should be preferred. ; Electronic supplementary material ; The online version of this article (doi:10.1186/s12874-017-0328-2) contains supplementary material, which is available to authorized users.
• Subjects:
  • Chronic Disease
  • Diabetes Mellitus, Type 2
  • Humans
  • Male
  • Mass Screening
• Source:
  BMC Med Res Methodol. 17.
• Pubmed ID:
  28399821
• Pubmed Central ID:
  PMC5387346
• Document Type:
  Journal Article
• Place as Subject:
  Denmark
• Volume:
  17
• Download URL:
  https://stacks.cdc.gov/view/cdc/45174/cdc_45174_DS1.pdf
• File Type:
  [PDF - 1.28 MB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:c705cbf28f2140e973d9ee7a23067086bcd6cd730f6e87ab7277bd7b3f79ac4b6f94b302411d44e0a8feef665b2c7f163a884e9b03a61783b733b523de55a96b