CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
IMMUNOPATHOLOGY OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION OF NEWBORN MICE
-
Apr 01 1968
-
Source: J Exp Med. 127(4):757-766.
Details:
-
Alternative Title:J Exp Med
-
Personal Author:
-
Description:Antithymocyte serum, when administered neonatally to mice, delayed the maturation of the lymphoid system, permitting development of cellular tolerance to LCM virus at an older age than is ordinarily possible. Humoral antibody formation was not prevented and the animals exhibited the paradox of high titers of both circulating virus and antibody. This, in turn, was followed by a chronic immunopathologic glomerulonephritis in most animals. Some animals developed wasting disease between 1 and 2 months of age, characterized by reticular cell hyperplasia and widespread infiltration into tissues and organs.
-
Subjects:
-
Source:
-
Pubmed ID:4868581
-
Pubmed Central ID:PMC2138472
-
Document Type:
-
Volume:127
-
Issue:4
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type: