National Healthcare Safety Network (NHSN) biovigilance component : hemovigilance module surveillance protocol
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National Healthcare Safety Network (NHSN) biovigilance component : hemovigilance module surveillance protocol

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      Purpose: The National Healthcare Safety Network (NHSN) Hemovigilance (HV) Module was created to implement national surveillance of transfusion-associated adverse events aimed at improving patient safety, minimizing morbidity and mortality of transfusion recipients, and identifying emerging complications and pathogens associated with blood transfusion.

      Settings: The Hemovigilance Module may be used by any U.S. healthcare facility where blood components and manufactured blood products are transfused (e.g., adult or pediatric facilities, acute or non-acute care facilities). Surveillance must be performed facility-wide, including patient care areas for emergency, general medical, and surgical patients; obstetrics and gynecology; orthopedics, oncology, and other chronic diseases; and any other facility location where transfusions are administered.

      Methods: The NHSN Hemovigilance Module requires comprehensive surveillance of patients and blood components throughout the transfusion process, from product receipt to administration to the patient. Participation in the NHSN Hemovigilance Module requires reporting of all adverse transfusion reactions and reaction-associated incidents that occur for patients transfused at or by your facility as well as a monthly summary of components transfused or discarded and patient samples collected for type and screen or crossmatch.

      Data Collection: NHSN is a web-based application used by healthcare facilities to report surveillance data. Paper versions of all forms are used to collect data prior to data entry in the NHSN Hemovigilance Module. The paper forms are available on the NHSN Blood Safety Surveillance website. A link to the appropriate form(s) and their instructions is provided in the following sections for your convenience.

      Training: Training presentations are available on the NHSN Biovigilance Component website for self-paced training and must be reviewed prior to participating in the Hemovigilance Module. CDC also provides webinar and in-person training opportunities for current NHSN participants. These opportunities are communicated through the NHSN quarterly newsletter and emails from the Biovigilance Team.

      Suggested citation for the Hemovigilance Module Surveillance Protocol: U.S. Centers for Disease Control and Prevention. The National Healthcare Safety Network (NHSN) Manual: Biovigilance Component v2.4. Atlanta, GA: Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases. Available at: Accessed [enter date].

      NHSN Biovigilance Component Hemovigilance Module Surveillance Protocol v2.4


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