Cardiometabolic Risk Factors Among 1.3 Million Adults With Overweight or Obesity, but Not Diabetes, in 10 Geographically Diverse Regions of the United States, 2012–2013

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Nichols, Gregory A. ; Horberg, Michael ; Koebnick, Corinna ; Young, Deborah Rohm ; Waitzfelder, Beth ; Sherwood, Nancy E. ; Daley, Matthew F. ; Ferrara, Assiamira
• Description:
  Introduction
  
  Various phenotypes of overweight and obesity pose various health risks. The objective of this study was to determine the prevalence of 4 commonly measured cardiometabolic risk factors (CRFs) among adults with overweight or obesity, but not diabetes, at the time of the study.
  
  Methods
  
  We analyzed data for 1,294,174 adults (aged ≥20 y) who were members of one of 4 integrated health systems. Each cohort member had a body mass index in 2012 or 2013 that indicated overweight or obesity. We determined the presence of 4 CRFs within 1 year of the first BMI measurement: elevated blood pressure (systolic ≥130 mm Hg or diastolic >85 mm Hg or ICD-9-CM [International Classification of Diseases, Ninth Revision, Clinical Modification] diagnosis code 401.0–405.9); elevated triglycerides (≥150 mg/dL or ICD-9-CM 272.1); low high-density lipoprotein cholesterol (<40 mg/dL for men or <50 mg/dL for women or ICD-9-CM 272.5); and prediabetes (fasting glucose 100–125 mg/dL or HbA1c 5.7%–6.4% or ICD-9-CM 790.2x). We tested the risk of having 1 or more CRFs after adjusting for obesity class and demographic characteristics with multivariable logistic regression.
  
  Results
  
  Among participants with overweight (52.5% of the sample), 18.6% had none of the 4 CRFs. Among the 47.5% of participants with obesity, 9.6% had none; among participants with morbid obesity, 5.8% had none. Age was strongly associated with CRFs in multivariable analysis.
  
  Conclusion
  
  Almost 10% of participants with obesity had no CRFs. Overweight or obesity increases cardiometabolic risk, but the number and type of CRFs varied substantially by age, even among participants with morbid obesity.
  
  
• Subjects:
  Adult Aged Aged, 80 And Over Cardiovascular Diseases Cohort Studies Female Health Surveys Humans Male Middle Aged Odds Ratio Overweight Risk Factors Young Adult

  More +
• Source:
  Prev Chronic Dis. 14.
• DOI:
  http://dx.doi.org/10.5888/pcd14.160438
• ISSN:
  1545-1151
• Pubmed ID:
  28278130
• Pubmed Central ID:
  PMC5345964
• Document Type:
  Journal Article
• Funding:
  P30 DK092924/DK/NIDDK NIH HHS/United States
• Place as Subject:
  United States
• Volume:
  14
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:65f484d4a57d929779c44856d8e18f8d1d41252ddb2e254d2b75aabaac325d2bfaa1d3eca445e31b786458dc5e0a1ee573e7047649fe1885316488f1674f1997
• Download URL:
  https://stacks.cdc.gov/view/cdc/44769/cdc_44769_DS1.pdf
• File Type:
  [PDF - 431.85 KB ]