Details:

Alternative Title:
BMC Public Health
Publisher's site:
http://dx.doi.org/10.1186/s12889-015-2179-2
Personal Author:
Kharsany, Ayesha B. M. ; Cawood, Cherie ; Khanyile, David ; Grobler, Anneke ; Mckinnon, Lyle R. ; ... More +
Kharsany, Ayesha B. M. ; Cawood, Cherie ; Khanyile, David ; Grobler, Anneke ; Mckinnon, Lyle R. ; Samsunder, Natasha ; Frohlich, Janet A. ; Abdool Karim, Quarraisha ; Puren, Adrian ; Welte, Alex ; George, Gavin ; Govender, Kaymarlin ; Toledo, Carlos ; Chipeta, Zawadi ; Zembe, Lycias ; Glenshaw, Mary T. ; Madurai, Lorna ; Varough M., Deyde ; Bere, Alfred ; Less -
Description:
Background South Africa has over 6,000,000 HIV infected individuals and the province of KwaZulu-Natal (KZN) is the most severely affected. As public health initiatives to better control the HIV epidemic are implemented, timely, detailed and robust surveillance data are needed to monitor, evaluate and inform the programmatic interventions and policies over time. We describe the rationale and design of the HIV Incidence Provincial Surveillance System (HIPSS) to monitor HIV prevalence and incidence. Methods/Design The household-based survey will include a sample of men and women from two sub-districts of the uMgungundlovu municipality (Vulindlela and the Greater Edendale) of KZN, South Africa. The study is designed as two sequential cross-sectional surveys of 10,000 randomly selected individuals aged 15–49 years to be conducted one year apart. From the cross sectional surveys, two sequential cohorts of HIV negative individuals aged 15–35 years will be followed-up one year later to measure the primary outcome of HIV incidence. Secondary outcomes include the laboratory measurements for pulmonary tuberculosis, sexually transmitted infections and evaluating tests for estimating population-level HIV incidence. Discussion The results from HIPSS will provide critical data regarding HIV prevalence and incidence in this community and will establish whether HIV prevention and treatment efforts in a “real world”, non-trial setting have an impact on HIV incidence at a population level. Importantly, the study design and methods will inform future methods for HIV surveillance.
Subject:
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Adolescent
Adult
Anti-HIV Agents
CD4 Lymphocyte Count
Cross-Sectional Studies
Family Characteristics
Female
HIV-1
HIV Infections
Humans
Incidence
Longitudinal Studies
Male
Middle Aged
Population Surveillance
Prevalence
Research Design
Residence Characteristics
Risk-Taking
Study Protocol
Viral Load
Young Adult

Source:
BMC Public Health. 15.
Pubmed ID:
26588902
Pubmed Central ID:
PMC4654918
Document Type:
Journal Article ;
Funding:
U2G GH000372/GH/CGH CDC HHS/United States ; 3U2GGH000372-02/PHS HHS/United States ; PEPFAR/United States ;
U2G GH000372/GH/CGH CDC HHS/United States ; 3U2GGH000372-02/PHS HHS/United States ; PEPFAR/United States ; Less -
Place as Subject:
South Africa ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:f7d8cdcf509afcf97ab6c874e7378f608c264dc91d5e088dbb7d79ed2ff14aeb
File Type:

Supporting Files

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