Guidance for U.S. laboratories testing for Zika virus infection
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Guidance for U.S. laboratories testing for Zika virus infection

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      Testing of specimens within the United States and U.S. territories to determine possible Zika virus infection should be limited to specimens collected from patients meeting CDC’s clinical and epidemiological criteria for testing1. Clinical signs and symptoms associated with Zika virus infection are discussed here: http://www.cdc.gov/zika/symptoms/index.html. It is important to note that Zika virus infection can cause signs and symptoms similar to those seen in patients with other arthropod-borne virus (arbovirus) infections, including dengue virus, a related flavivirus, and chikungunya virus, an unrelated alphavirus. It is also important to note that a positive result for one of these viruses does not preclude infection with the others. Co-infection with Zika virus and dengue or chikungunya viruses is rare, but possible. Current general information and guidance for the U.S. Zika response is available on CDC’s Zika website at http://www.cdc.gov/zika/index.html. Information specific to laboratories is available at http://www.cdc.gov/zika/laboratories/index.html. Current information and guidance specific to Zika virus in Puerto Rico can be found at the Puerto Rico Department of Health website: http://www.salud.gov.pr/Sobre-tu-Salud/Pages/Condiciones/Zika.aspx. laboratory-guidance-zika.pdf
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