Factors associated with recurrent tuberculosis more than 12 months after treatment completion

Details

• Alternative Title:
  Int J Tuberc Lung Dis
• Personal Author:
  Kim, Lindsay ; Moonan, Patrick K. ; Heilig, Charles M. ; Yelk Woodruff, Rachel S. ; Kammerer, J. Steve ; Haddad, Maryam B.
• Description:
  Setting ; Even in persons with complete treatment of their first tuberculosis (TB) episode, patients with a TB history are at higher risk for having TB. ; Objective ; Describe factors from the initial TB episode associated with recurrent TB among patients who completed treatment and remained free of TB for at least 12 months. ; Design ; US TB cases, stratified by birth origin, during 1993-2006 were examined. Cox proportional hazards regression was employed to assess the association of factors during the initial episode with recurrence at least 12 months after treatment completion. ; Results ; Among 632 US-born patients, TB recurrence was associated with age 25-44 (adjusted hazard ratio aHR 1.77, 99% confidence interval CI 1.02-3.09, attributable fraction AF 1%-34%), substance use (aHR 1.57, 99%CI 1.23-2.02, AF 8%-22%), and treatment supervised by health departments (aHR 1.42, 99%CI 1.03-1.97, AF 2%-28%). Among 211 foreign-born patients, recurrence was associated with HIV infection (aHR 2.24, 99%CI 1.27-3.98, AF 2%-9%) and smear-positive TB (aHR 1.56, 99%CI 1.06-2.30, AF 3%-33%). ; Conclusion ; Factors associated with recurrence differed by birth origin and might be useful for anticipating greater risk for recurrent TB among certain patients with a TB history.
• Subjects:
  • Adolescent
  • Adult
  • Aged
  • Antitubercular Agents
  • Child
  • Child, Preschool
  • Cohort Studies
  • Female
  • Humans
  • Infant
  More +
• Source:
  Int J Tuberc Lung Dis. 20(1):49-56
• Pubmed ID:
  26688528
• Pubmed Central ID:
  PMC5082738
• Document Type:
  Text
• Funding:
  CC999999/Intramural CDC HHS/United States
• Genre:
  Journal Article
• Place as Subject:
  United States
• Volume:
  20
• Issue:
  1
• Download URL:
  https://stacks.cdc.gov/view/cdc/42299/cdc_42299_DS1.pdf
• File Type:
  [PDF - 292.56 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:c70b683824015678a6e169e107e1f0e05bd34f2275df0bd8101793778bc50850e8f5c0a90672838307075b6dc467180274164c9f776a7a158a36f393c8e2fa7a