Clinician Perspectives on Using Pharmacogenomics in Clinical
Practice

Unertl, Kim M.; Jaffa, Habiba; Field, Julie R.; Price, Lisa; Peterson, Josh F.

doi:10.2217/pme.15.10

i

Clinician Perspectives on Using Pharmacogenomics in Clinical Practice

Supporting Files

2015
By Unertl, Kim M. ; Jaffa, Habiba ; Field, Julie R. ; ...

File Language:

English

Details

Alternative Title:

Per Med
Personal Author:

Unertl, Kim M. ; Jaffa, Habiba ; Field, Julie R. ; Price, Lisa ; Peterson, Josh F.
Description:

Aim

To describe the knowledge and attitudes of clinicians participating in a large pharmacogenomics implementation program.

Materials & methods

Semi-structured interviews with 15 physicians and nurse practitioners were conducted.

Results

Three categories of themes were identified: preparation and knowledge, pharmacogenomics usage in practice, and future management of genomic variants. Providers expressed an inability to keep up with the rapid pace of evidence generation and indicated strong support for clinical decision support to assist with genotype-tailored therapies. Concerns raised by clinicians included effectively communicating results, long-term responsibility for actionable results and hand-offs with providers outside the implementation program.

Conclusions

Clinicians identified their own knowledge deficits, workflow integration, and longitudinal responsibility as challenges to successful usage of pharmacogenomics in clinical practice.
Keywords:

Attitudes Personalized Medicine Pharmacogenomics Qualitative Research Translational Research
Source:

Per Med. 12(4):339-347
Pubmed ID:

26635887
Pubmed Central ID:

PMC4664195
Document Type:

Journal Article
Funding:

U01 HL105198/HL/NHLBI NIH HHSUnited States/ ; U01 HL122904/HL/NHLBI NIH HHSUnited States/ ; U19 HL065962/HL/NHLBI NIH HHSUnited States/ ; U47 CI000824/CI/NCPDCID CDC HHSUnited States/ ; U01 HG006378/HG/NHGRI NIH HHSUnited States/ ; U01 HG007253/HG/NHGRI NIH HHSUnited States/ ; UL1 TR000445/TR/NCATS NIH HHSUnited States/
Volume:

12
Issue:

4
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:6e1da0ce90d7dc398474eb41655e4ecd44aa2ac7d0c58cd9738058c28c08be30
Download URL:

https://stacks.cdc.gov/view/cdc/42083/cdc_42083_DS1.pdf
File Type:

[PDF - 83.19 KB ]

nihms669644.nxml

Download xml

File Language:

English

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