Cervical Cancer Prevention in HIV-infected Women Using the “See and Treat” Approach in Botswana

Details

• Alternative Title:
  J Acquir Immune Defic Syndr
• Personal Author:
  Ramogola-Masire, Doreen ; de Klerk, Ronny ; Monare, Barati ; Ratshaa, Bakgaki ; Friedman, Harvey M. ; Zetola, Nicola M.
• Description:
  Background
  
  Cervical cancer is a major public health problem in resource-limited settings, particularly among HIV-infected women. Given the challenges of cytology-based approaches, the efficiency of new screening programs need to be assessed.
  
  Setting
  
  Community and hospital-based clinics in Gaborone, Botswana.
  
  Objective
  
  To determine the feasibility, and efficiency of the “See and Treat” approach using Visual Inspection Acetic Acid (VIA) and Enhanced Digital Imaging (EDI) for cervical cancer prevention in HIV-infected women.
  
  Methods
  
  A two-tier community-based cervical cancer prevention program was implemented. HIV-infected women were screened by nurses at the community using the VIA/EDI approach. Low-grade lesions were treated with cryotherapy on the same visit.
  
  Results
  
  From March 2009 through January 2011, 2,175 patients were screened for cervical cancer at our community-based clinic. 253 (11.6%) were found to have low-grade lesions and received same-day cryotherapy. 1,347 (61.9%) women were considered to have a normal examination and 575 (27.3%) were referred for further evaluation and treatment. Of the 1,347 women initially considered to have normal exams, 267 (19.8%) were recalled based on weekly quality control assessments. 210 (78.6%) of the 267 recalled women and 499 (86.8%) of the 575 referred women were seen at the referral clinic. Of these 709 women, 506 (71.4%) required additional treatment. Overall, 264 CIN stage 2 or 3 were identified and treated, and six micro-invasive cancers identified were referred for further management.
  
  Conclusions
  
  Our “See and Treat” cervical cancer prevention program using the VIA/EDI approach is a feasible, high-output and high-efficiency program, worthy of considering as an additional cervical cancer screening method in Botswana, especially for women with limited access to the current cytology-based screening services.
  
  
• Subjects:
  Acetic Acid Cervical Intraepithelial Neoplasia Cryotherapy Female HIV HIV Infections Humans Statistics, Nonparametric Urban Population Uterine Cervical Neoplasms
• Source:
  J Acquir Immune Defic Syndr. 2013; 59(3).
• Pubmed ID:
  22134146
• Pubmed Central ID:
  PMC3884088
• Document Type:
  Journal Article
• Funding:
  P30 AI045008/AI/NIAID NIH HHS/United States ; U2G PS001949/PS/NCHHSTP CDC HHS/United States ; 1U2GPS001949/PHS HHS/United States ; IP30 AI 45008/AI/NIAID NIH HHS/United States
• Place as Subject:
  Botswana
• Volume:
  59
• Issue:
  3
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:48fa6f6cf8cb2a2946c685a28b3e4ab621921c87054e9a866b7e622d92298775
• Download URL:
  https://stacks.cdc.gov/view/cdc/41937/cdc_41937_DS1.pdf
• File Type:
  [PDF - 251.01 KB ]