Loss of Anatomical Landmarks with Eutectic Mixture of Local Anesthetic Cream for Neonatal Male Circumcision

Details

• Alternative Title:
  J Pediatr Urol
• Personal Author:
  Plank, Rebeca M. ; Kubiak, David W. ; Abdullahi, Rasak Bamidele ; Ndubuka, Nnamdi ; Nkgau, Maggie M. ; Dapaah-Siakwan, Fredrick ; Powis, Kathleen M. ; Lockman, Shahin
• Description:
  We report two cases of newborns who developed marked local edema after application of a eutectic mixture of local anesthetic (EMLA) topical anesthetic cream for neonatal male circumcision (NMC). Although local edema and erythema are known potential side effects of EMLA cream, a common anesthetic used for NMC, the loss of landmarks precluding safe NMC has not previously been reported, and is described here. Although we cannot recommend an alternate local anesthetic for neonates with this reaction to EMLA, based on a review of the published data we think that serious systemic adverse events related to EMLA are extremely rare.
• Subjects:
  Administration, Topical Anatomic Landmarks Circumcision, Male Edema Foreskin Humans Infant, Newborn Lidocaine Male Prilocaine Skin Cream

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• Source:
  J Pediatr Urol. 2012; 9(1):e86-e90.
• Pubmed ID:
  23102766
• Pubmed Central ID:
  PMC3568457
• Document Type:
  Journal Article
• Funding:
  K23 AI084579/AI/NIAID NIH HHS/United States ; K23 HD070774/HD/NICHD NIH HHS/United States ; U2G PS000941/PS/NCHHSTP CDC HHS/United States ; 5K23AI084579/AI/NIAID NIH HHS/United States
• Volume:
  9
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:508ae94d323279c468db53a02e013418edaeb42eb8ee5b66801c33add7c5a303
• Download URL:
  https://stacks.cdc.gov/view/cdc/41877/cdc_41877_DS1.pdf
• File Type:
  [PDF - 579.85 KB ]