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Tuberculosis screening outcomes for newly diagnosed persons living with HIV, Nyanza Province, Kenya, 2009
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Details:
  • Pubmed ID:
    26688532
  • Pubmed Central ID:
    PMC5055834
  • Funding:
    U19 GH000041/GH/CGH CDC HHS/United States
    5U19GH000041/GH/CGH CDC HHS/United States
    PEPFAR/United States
  • Document Type:
  • Collection(s):
  • Description:
    SETTING

    Fifteen human immunodeficiency virus (HIV) clinics in Nyanza Region, Western Kenya.

    OBJECTIVE

    To describe routine tuberculosis (TB) screening and diagnostic practices among newly enrolled people living with HIV (PLHIV) prior to the implementation of World Health Organization recommended TB intensified case finding.

    DESIGN

    Retrospective chart abstraction of PLHIV aged ⩾7 years who were newly enrolled in HIV care in July and August 2009, and who had not received antiretroviral treatment in the preceding 2 years or been diagnosed with TB in the previous year. Factors associated with evidence of TB diagnostic evaluation among symptomatic PLHIV were assessed.

    RESULTS

    Of 1020 patients included in the analysis, 995 (98%) were screened for TB at enrolment and 613 (62%) reported TB symptoms. Ninety-six (16%) patients with symptoms had evidence of referral for TB diagnostic evaluation, including patients at large clinics, those with advanced HIV disease and those reporting multiple TB symptoms. Among the 43 (45%) with documented evaluation results, 26 (60%) were diagnosed with TB.

    CONCLUSION

    Although most PLHIV were screened for TB, very few underwent an evaluation, and the proportion diagnosed with TB was very low. Efforts to improve TB screening should focus on standardizing the intensified case finding algorithm and linkage to, and adequate infrastructure for, TB diagnostic evaluation.