CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Diet, physical activity and mental health status are associated with dysglycaemia in pregnancy: The Healthy Start Study
-
Mar 03 2016
-
-
Source: Diabet Med. 33(5):663-667.
[PDF-162.53 KB]
Details:
-
Alternative Title:Diabet Med
-
Personal Author:
-
Description:Aims
Prenatal dysglycaemia is associated with adverse maternal and offspring outcomes. This study examined the association between dysglycaemia and multiple modifiable factors measured during pregnancy.
Methods
The Healthy Start Study collected self-reported data on modifiable factors in early and mid-pregnancy (median 17 and 27 weeks gestation, respectively) from 832 women. Women received 1 point for each optimal modifiable factor: diet quality (Healthy Eating Index ≥64), physical activity level (estimated energy expenditure ≥170 MET-hours/week), and mental health status (Perceived Stress <6 and Edinburgh Postnatal Depression <13). Dysglycaemia during pregnancy was defined as an abnormal glucose challenge, ≥1 abnormal results on an oral glucose tolerance test, or a clinical diagnosis of gestational diabetes. Logistic regression models estimated odds ratios for dysglycaemia as a function of each factor and the total score, adjusted for age, race/ethnicity, pre-pregnant body mass index, history of gestational diabetes, and family history of type 2 diabetes.
Results
In individual analyses, only physical activity was significantly associated with a reduced risk of dysglycaemia (adjusted OR 0.67, 95%CI 0.44–1.00). We observed a significant, dose-response association between increasing numbers of optimal factors and odds of dysglycaemia (adjusted p=0.01). Compared to having no optimal modifiable factors, having all 3 was associated with a 73% reduced risk of dysglycaemia (adjusted OR 0.27, 95%CI 0.08–0.95).
Conclusions
An increasing number of positive modifiable factors in pregnancy was associated with a dose-response reduction in risk of dysglycaemia. Our results support the hypothesis that modifiable factors in pregnancy are associated with the risk of prenatal dysglycaemia.
-
Subjects:
-
Source:
-
Pubmed ID:26872289
-
Pubmed Central ID:PMC4883104
-
Document Type:
-
Funding:
-
Name as Subject:
-
Place as Subject:
-
Volume:33
-
Issue:5
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
