An automatic experimental apparatus to study arm reaching in New World monkeys

Details

• Alternative Title:
  J Neurosci Methods
• Personal Author:
  Yin, Allen ; An, Jehi ; Lehew, Gary ; Lebedev, Mikhail A. ; Nicolelis, Miguel A. L.
• Description:
  Background ; Several species of the New World monkeys have been used as experimental models in biomedical and neurophysiological research. However, a method for controlled arm reaching tasks has not been developed for these species. ; New Method ; We have developed a fully automated, pneumatically driven, portable, and reconfigurable experimental apparatus for arm-reaching tasks suitable for these small primates. ; Results ; We have utilized the apparatus to train two owl monkeys in a visually-cued arm-reaching task. Analysis of neural recordings demonstrates directional tuning of the M1 neurons. ; Comparison with Existing Method(s) ; Our apparatus allows automated control, freeing the experimenter from manual experiments. ; Conclusion ; The presented apparatus provides a valuable tool for conducting neurophysiological research on New World monkeys.
• Subjects:
  • Animals
  • Aotidae
  • Arm
  • Behavior, Animal
  • Electrophysiological Phenomena
  • Equipment Design
  • Female
  • Models, Animal
  • Motor Cortex
  • Neurons
  More +
• Source:
  J Neurosci Methods. 264:57-64.
• Pubmed ID:
  26928257
• Pubmed Central ID:
  PMC4839179
• Document Type:
  Journal Article
• Funding:
  DP1 MH099903/MH/NIMH NIH HHS/United States ; DP1MH099903/DP/NCCDPHP CDC HHS/United States
• Volume:
  264
• Download URL:
  https://stacks.cdc.gov/view/cdc/40927/cdc_40927_DS1.pdf
• File Type:
  [PDF - 961.52 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:1d86b8ae12f2a180cff70eda0c76a1207f96ff48df9eb2be28ebe7f8660146e5