Population impact of preterm birth and low birth weight on developmental disabilities in US children

Details

• Alternative Title:
  Ann Epidemiol
• Personal Author:
  Schieve, Laura A. ; Tian, Lin H. ; Rankin, Kristin ; Kogan, Michael D. ; Yeargin-Allsopp, Marshalyn ; Visser, Susanna ; Rosenberg, Deborah
• Description:
  Purpose
  
  Although previous studies demonstrate associations between adverse perinatal outcomes and developmental disabilities (DDs), study of population impacts is limited.
  
  Methods
  
  We computed relative risks adjusted (aRRs) for sociodemographic factors and component and summary population attributable fractions (PAFs) for associations between very low birth weight (VLBW, all preterm births), moderately low birth weight (MLBW) + Preterm, MLBW at term, and normal birth weight (NBW) + Preterm and seven DDs (cerebral palsy [CP], autism spectrum disorder [ASD], intellectual disability [ID], behavioral-conduct disorders, attention-deficit-hyperactivity disorder [ADHD], learning disability [LD], and other developmental delay) among children aged 3–17 years in the 2011–2012 National Survey of Children’s Health.
  
  Results
  
  VLBW-Preterm, MLBW-Preterm and NBW-Preterm were strongly to moderately associated with CP (aRRs: 43.5, 10.1, and 2.2, respectively; all significant) and also associated with ID, ASD, LD, and other developmental delay (aRR ranges: VLBW-Preterm 2.8–5.3; MLBW-Preterm 1.9–2.8; and NBW-Preterm 1.6–2.3). Summary PAFs for preterm birth and/or LBW were 55% for CP, 10%–20% for ASD, ID, LD, and other developmental delay, and less than 5% for ADHD and behavioral-conduct disorders. Findings were similar whether we assessed DDs as independent outcomes or within mutually exclusive categories accounting for DD co-occurrence.
  
  Conclusions
  
  Preterm birth has a sizable impact on child neurodevelopment. However, relative associations and population impacts vary widely by DD type.
  
  
• Subjects:
  Adolescent Birth Weight Child Child, Preschool Developmental Disabilities Female Follow-Up Studies Gestational Age Humans Incidence Infant, Low Birth Weight Male Maternal Age Population Surveillance Pregnancy Premature Birth Risk Factors Socioeconomic Factors

  More +
• Source:
  Ann Epidemiol. 26(4):267-274.
• Pubmed ID:
  27085382
• Pubmed Central ID:
  PMC4978423
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  26
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:59c43789b8dec009a2aaabcc08a85c8b0ad543aa3b5d4f088ae79a78136d3e39
• Download URL:
  https://stacks.cdc.gov/view/cdc/40744/cdc_40744_DS1.pdf
• File Type:
  [PDF - 358.58 KB ]