Impact of two rounds of praziquantel mass drug administration on Schistosoma mansoni infection prevalence and intensity: a comparison between community wide treatment and school based treatment in western Kenya

Onkanga, Isaac O.; Mwinzi, Pauline N.M.; Muchiri, Geoffrey; Andiego, Kennedy; Omedo, Martin; Karanja, Diana M.S.; Wiegand, Ryan E.; Secor, W. Evan; Montgomery, Susan P.

doi:10.1016/j.ijpara.2016.01.006

i

Impact of two rounds of praziquantel mass drug administration on Schistosoma mansoni infection prevalence and intensity: a comparison between community wide treatment and school based treatment in western Kenya

Supporting Files Public Domain

Mar 02 2016
By Onkanga, Isaac O. ; Mwinzi, Pauline N.M. ; Muchiri, Geoffrey ; ...

File Language:

English

Details

Alternative Title:

Int J Parasitol
Personal Author:

Onkanga, Isaac O. ; Mwinzi, Pauline N.M. ; Muchiri, Geoffrey ; Andiego, Kennedy ; Omedo, Martin ; Karanja, Diana M.S. ; Wiegand, Ryan E. ; Secor, W. Evan ; Montgomery, Susan P.
Description:

This study compared the effectiveness of the community-wide treatment and school-based treatment approaches in the control of Schistosoma mansoni infections in villages with ⩾25% prevalence in western Kenya. Stool samples from first year students, 9-12year olds and adults (20-55years) were analyzed by the Kato-Katz technique for S. mansoni eggs. After two rounds of treatment, S. mansoni prevalence and intensity levels significantly declined in both treatment approaches. Prevalence comparisons between the two approaches did not show any significant differences following treatment. However, infection intensity levels in the 9-12year old school-attending pupils were significantly higher in the community-wide treatment arm than in the school-based treatment arm. Nevertheless, significant reductions in S. mansoni infection prevalence and intensity levels were achieved among school-age children regardless of the treatment approach used.
Subjects:

Adolescent Adult Anthelmintics Child Child, Preschool Delivery Of Health Care Feces Humans Middle Aged Parasite Egg Count Praziquantel Prevalence Schistosomiasis Mansoni School Health Services Young Adult
Source:

Int J Parasitol. 46(7):439-445.
Pubmed ID:

26940547
Pubmed Central ID:

PMC4920687
Document Type:

Journal Article
Place as Subject:

Kenya
Volume:

46
Issue:

7
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:51293562bfac548eb4de1f518d59f0a58f6bcd66d4ea57c43cc02164a36e5cf5
Download URL:

https://stacks.cdc.gov/view/cdc/40460/cdc_40460_DS1.pdf
File Type:

[PDF - 367.96 KB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.