Advances in Identifying Beryllium Sensitization and Disease

Details

• Alternative Title:
  Int J Environ Res Public Health
• Personal Author:
  Middleton, Dan ; Kowalski, Peter
• Description:
  Beryllium is a lightweight metal with unique qualities related to stiffness, corrosion resistance, and conductivity. While there are many useful applications, researchers in the 1930s and 1940s linked beryllium exposure to a progressive occupational lung disease. Acute beryllium disease is a pulmonary irritant response to high exposure levels, whereas chronic beryllium disease (CBD) typically results from a hypersensitivity response to lower exposure levels. A blood test, the beryllium lymphocyte proliferation test (BeLPT), was an important advance in identifying individuals who are sensitized to beryllium (BeS) and thus at risk for developing CBD. While there is no true "gold standard" for BeS, basic epidemiologic concepts have been used to advance our understanding of the different screening algorithms.
• Subjects:
  BeLPT Berylliosis Beryllium Beryllium Sensitization BeS CBD Chronic Beryllium Disease Humans Models, Theoretical Probability Theory Review Screening

  More +
• Source:
  Int J Environ Res Public Health. 2010; 7(1):115-124.
• Document Type:
  Journal Article
• Volume:
  7
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:71a9f86dcd74b8b1d982bda7a9078ae8ccacbc11c30c073db5e85aee53ed2bab
• Download URL:
  https://stacks.cdc.gov/view/cdc/4013/cdc_4013_DS1.pdf
• File Type:
  [PDF - 302.81 KB ]