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Use? A Novel Study Design Incorporating Semen Biomarkers
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Aug 07 2011
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Source: Infect Dis Obstet Gynecol. 2011; 2011.
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Alternative Title:Infect Dis Obstet Gynecol
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Description:Long-acting reversible contraceptive (LARC) methods are highly effective against pregnancy. A barrier to their widespread promotion can include the concern they will lead reduced condom use and, thus, will put couples at higher risk for sexually transmitted infections (STIs). We review evidence from previous studies of condom "migration" associated with the use of LARC and propose a novel study design to address the two main methodological issues that have limited these earlier studies. Namely, we propose to use a randomized controlled trial design and to use a biological marker of semen exposure for measuring changes in condom use.
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