Shiftwork and Diurnal Salivary Cortisol Patterns Among Police Officers

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Charles, Luenda E. ; Fekedulegn, Desta ; Burchfiel, Cecil M. ; Hartley, Tara A. ; Andrew, Michael E. ; Violanti, John M. ; Miller, Diane B.
• Description:
  Objective ; To investigate associations between shiftwork and diurnal salivary cortisol among 319 police officers (77.7% men) ; Methods ; Information on shiftwork was obtained from the City of Buffalo, NY electronic payroll records. Saliva was collected using Salivettes at seven time points and analyzed for free cortisol concentrations (nmol/L) using a chemiluminescence immunoassay. Mean slopes and areas under the curve were compared across shift schedule using analysis of variance (ANOVA)/analysis of covariance (ANCOVA). ; Results ; Officers working primarily on the night shift had a significantly shallower slope. Mean slope (nmol/L/minutes) of the cortisol curve varied significantly across shifts (day: −0.00332 ± 0.00017, afternoon: −0.00313 ± 0.00018, night: −0.00257 ± 0.0002); adjusted P = 0.023. ; Conclusions ; Our results suggest that night shiftwork is a work-place factor that may alter the response of the hypothalamic–pituitary–adrenal (HPA) axis to the circadian cues responsible for the pattern of the diurnal cortisol curve.
• Subjects:
  • Adult
  • Aged
  • Analysis of Variance
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hydrocortisone
  • Male
  • Middle Aged
  • Occupational Health
  More +
• Source:
  J Occup Environ Med. 58(6):542-549.
• Pubmed ID:
  27129020
• Pubmed Central ID:
  PMC4909046
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  New York
• Volume:
  58
• Issue:
  6
• Download URL:
  https://stacks.cdc.gov/view/cdc/39980/cdc_39980_DS1.pdf
• File Type:
  [PDF - 224.09 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:19bbbeba9806007dd294eac9093f08185fba61317b9af3047851a96a88899028