Details:

Alternative Title:
Genome Med
Personal Author:
Guessous, Idris ; Gwinn, Marta ; Khoury, Muin J ;
Guessous, Idris ; Gwinn, Marta ; Khoury, Muin J ; Less -
Description:
Despite large public investments in genome-wide association studies of common human diseases, so far, few gene discoveries have led to applications for clinical medicine or public health. Genome-wide association studies in the context of clinical trials of drug safety and efficacy may be quicker to yield clinical applications. Certain methodological concerns, such as selection bias and confounding, may be mitigated when genome-wide association studies are conducted within clinical trials, in which randomization of exposure, prospective evaluation of outcome and careful definition of phenotype are incorporated by design.
Subject:
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Commentary

Source:
Genome Med. 2009 ; 1(4):46.;
Document Type:
Journal Article ;
Collection(s):
CDC Public Access
Main Document Checksum:
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urn:sha256:5c6c508b830f6ebbeecf151734a3708eef06c8649adb64ec4eb27236d2ff8c75
File Type:

Supporting Files

• 	gm46-1.gif	gif
  	gm46-1.jpg	jpeg
  	gm46.nxml	txt
  	license.txt	txt

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