Alert to U.S. healthcare facilities : first mcr-1 gene in E. coli bacteria found in a human in the United States

Details

• Corporate Authors:
  Centers for Disease Control and Prevention (U.S.)
• Description:
  June 13, 2016, 13:35 EDT (1:35 PM EDT)
  
  CDCHAN-00390
  
  The Centers for Disease Control and Prevention (CDC) is collaborating in a coordinated public health
  
  response to the Department of Defense (DoD) announcement on May 26 of the first mcr-1 gene found in bacteria from a human in the United States (http://aac.asm.org/content/early/2016/05/25/AAC.01103-16.full.pdf+html). Escherichia coli (E. coli) bacteria carrying the mcr-1 gene were found in a urine sample from a person in Pennsylvania with no recent travel outside of the United States who presented to a clinic with a urinary tract infection. The mcr-1 gene makes bacteria resistant to the antibiotic colistin, which is used as a last-resort drug to treat patients with infections caused by multidrug-resistant bacteria, including carbapenem-resistant Enterobacteriaceae (CRE). The mcr-1 gene exists on a plasmid, a small piece of DNA that is capable of moving from one bacterium to another, potentially spreading antibiotic resistance to other bacterial species. CDC is issuing this HAN notice as a reminder to U.S. healthcare facilities about recommendations to prevent antibiotic resistant infections and alert them to additional recommendations for detecting and reporting bacteria with the mcr-1 gene.
  
  FINAL HAN 390_First mcr-1 Gene in E. coli in Human in US_06 13 2016.pdf
  
  
• Subjects:
  Drug Resistance, Bacterial Escherichia Coli/drug Effects Escherichia Coli Infections
• Source:
  HAN ; 390
• Series:
  Health Alert Network
• Document Type:
  HAN Health Advisory
• Place as Subject:
  United States
• Pages in Document:
  3 unnumbered pages
• Issue:
  390
• Collection(s):
  Health Alert Network (HAN)
• Main Document Checksum:
  urn:sha-512:c93d488f5674b0840a35138ffbf036fca2bf1570b441e66196a1da615326afccc7ae7d5ba6c5219dedf48266cb08e2b0f8dec0d9ce37bd2aef503205f73c40e5
• Download URL:
  https://stacks.cdc.gov/view/cdc/39870/cdc_39870_DS1.pdf
• File Type:
  [PDF - 62.38 KB ]