Alert to U.S. Healthcare Facilities: First Mcr-1 Gene in E. coli Bacteria Found in a Human in the United States [June 13, 2016, 13:35 EDT (1:35 PM EDT)]

Details

• Corporate Authors:
  Centers for Disease Control and Prevention (U.S.). Health Alert Network (HAN)
• Description:
  June 13, 2016, 13:35 EDT (1:35 PM EDT)
  
  CDCHAN-00390
  
  The Centers for Disease Control and Prevention (CDC) is collaborating in a coordinated public health
  
  response to the Department of Defense (DoD) announcement on May 26 of the first mcr-1 gene found in bacteria from a human in the United States (http://aac.asm.org/content/early/2016/05/25/AAC.01103-16.full.pdf+html). Escherichia coli (E. coli) bacteria carrying the mcr-1 gene were found in a urine sample from a person in Pennsylvania with no recent travel outside of the United States who presented to a clinic with a urinary tract infection. The mcr-1 gene makes bacteria resistant to the antibiotic colistin, which is used as a last-resort drug to treat patients with infections caused by multidrug-resistant bacteria, including carbapenem-resistant Enterobacteriaceae (CRE). The mcr-1 gene exists on a plasmid, a small piece of DNA that is capable of moving from one bacterium to another, potentially spreading antibiotic resistance to other bacterial species. CDC is issuing this HAN notice as a reminder to U.S. healthcare facilities about recommendations to prevent antibiotic resistant infections and alert them to additional recommendations for detecting and reporting bacteria with the mcr-1 gene.
  
  FINAL HAN 390_First mcr-1 Gene in E. coli in Human in US_06 13 2016.pdf
  
  
• Content Notes:
  Notice of Possible Alert Expiration: The CDC Health Alert, Advisory, Update, and Info Service announcements, distributed by the Health Alert Network (HAN), were active on the date they were originally published. Publication dates have been added to Titles for clarity. A CDC Health Alert, Advisory, Update, and Info Service announcement may expire at any time. They may also be updated or superseded according to later developments. None of the CDC Health Alert, Advisory, Update, or Info Service announcements in the Stacks HAN Collection should be assumed to be current or active. Stacks preserves HAN announcements in order to maintain a record of past CDC actions. Stacks in not designed for up-to-the-minute notifications. For the list of current CDC Health Alert, Advisory, Update, or Info Service announcements, patrons should visit the Health Alert Network (HAN) webpage at https://www.cdc.gov/han/php/about/index.html. For up to the minute reports, subscribe to the HAN email alert system hosted by CDC News & Updates at https://tools.cdc.gov/campaignproxyservice/subscriptions.aspx?topic_id=USCDC_486
  
  Categories of Health Alert Network (HAN) messages:
  
  Health Alert: Requires immediate action or attention, highest level of importance.
  
  Health Advisory: May not require immediate action; provides important information for a specific incident or situation.
  
  Health Update: Unlikely to require immediate action; provides updated information regarding an incident or situation.
  
  HAN Info Service: Does not require immediate action; provides general public health information.
  
  
• Subjects:
  Drug Resistance, Bacterial Escherichia Coli/drug Effects Escherichia Coli Infections
• Keywords:
  HAN Health Alert Network
• Source:
  HAN ; 390
• Series:
  Health Alert Network
• Subseries:
  CDC Health Advisory
• Publisher:
  Centers for Disease Control and Prevention (CDC) (U.S.)
• Document Type:
  Text
• Genre:
  Alert
• Place as Subject:
  United States
• Rights:
  Public Domain
• Pages in Document:
  3 unnumbered pages
• Issue:
  00390
• Collection(s):
  Health Alert Network (HAN)
• Main Document Checksum:
  urn:sha-512:c93d488f5674b0840a35138ffbf036fca2bf1570b441e66196a1da615326afccc7ae7d5ba6c5219dedf48266cb08e2b0f8dec0d9ce37bd2aef503205f73c40e5
• Download URL:
  https://stacks.cdc.gov/view/cdc/39870/cdc_39870_DS1.pdf
• File Type:
  [PDF - 62.38 KB ]