Ethical Considerations, Confidentiality Issues, Rights of Human Subjects, and Uses of Monitoring Data in Research and Regulation

Details

• Journal Article:
  Environmental Health Perspectives
• Personal Author:
  Schulte, Paul A. ; Haring Sweeney, Marie
• Description:
  The process of conducting research on human biomarkers was reviewed, and the ethical issues that arise at each step in the process were addressed. Some potential problems which arise and stimulate attempts in discovering approaches to solve the problems were presented. Emphasis was placed on design of studies, subject recruitment and informed consent, privacy and confidentiality, interpretation and communication of test and study results, communication to control subjects, responsibilities for action, dilemmas for researchers, and implications of biotechnologic developments. In almost every facet of human biomarker research studies, ethical issues have been involved. A number of concerns also have arisen when considering the use of human biologic specimens and new biomarkers. While it may seem that use of such markers taken from human specimens should be more accurate than traditional sources of information such as questionnaires or environmental monitoring, the authors caution that this is not necessarily the case. Issues which remain to be resolved include the use of specimens for purposes other than that for which they were collected, the extent of reporting back results, ownership of specimens, and use and interpretation of results. [Description provided by NIOSH]
• Subjects:
  Biological Markers Biological Products Biological Specimen Banks Confidentiality Environmental Monitoring Epidemiology Ethics, Medical Ethics, Research Genetic Testing Hematologic Tests Human Experimentation Human Rights Informed Consent Occupational Health Research Risk Assessment Safety Urine

  More +
• Keywords:
  NIOSH-Author; Risk-analysis; Epidemiology; Biological-monitoring; Urinalysis; Blood-analysis; Biological-material
• Source:
  Environ Health Perspect 1995 Apr; 103(Suppl 3):69-74
• ISSN:
  0091-6765
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  6 pdf pages
• Volume:
  103
• NIOSHTIC Number:
  nn:00229244
• Federal Fiscal Year:
  1995
• Peer Reviewed:
  True
• Collection(s):
  National Institute for Occupational Safety and Health CDC Public Access
• Main Document Checksum:
  urn:sha-512:8d92925d333e106bbc3da73c5357616564117bdcf0289fe52bddcebee30d1e39269b8b23647a9c0a98d7974631eb78e7570bd633f62b26dfa63544dfbde89f32
• Download URL:
  https://stacks.cdc.gov/view/cdc/3948/cdc_3948_DS1.pdf
• File Type:
  [PDF - 1.32 MB ]