Details:

Alternative Title:
Curr Fungal Infect Rep
Personal Author:
Nalintya, Elizabeth ; Kiggundu, Reuben ; Meya, David ;
Nalintya, Elizabeth ; Kiggundu, Reuben ; Meya, David ; Less -
Description:
Over the last decade, an upsurge in both the frequency and severity of fungal infections due to the HIV/AIDS epidemic and the use of immunosuppressive therapy has occurred. Even diagnostic methods like culture and microscopy, which have low sensitivity and longer turn-around-times are not widely available, leading to delays in timely antifungal therapy and detrimental patient outcomes. The evolution of cryptococcal antigen (CrAg) testing to develop inexpensive and more sensitive methods to detect cryptococcal antigen is significant. These newer tests employ immunoassays as part of point-of-care platforms, which do not require complex laboratory infrastructure and they have the potential to detect early disease and reduce time to diagnosis of cryptococcal infection. Advocacy for widely available and efficacious life-saving antifungal treatment should be the only remaining challenge.
Subject:
[+]
Antigen
Article
Assay
Cryptococcal Disease
Cryptococcal Meningitis
Cryptococcus
Diagnosis
Fungus
HIV
Lateral Flow
Testing
Thermal Contrast

Source:
Curr Fungal Infect Rep. 10(2):62-67 ;
Pubmed ID:
27158322
Pubmed Central ID:
PMC4858186
Document Type:
Journal Article ;
Funding:
U01 GH000517/GH/CGH CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:37591f0bedd21496293918d6a615ee7232295434d2932700501ff1bc1f692f86
File Type:

Supporting Files

• nihms-777332.nxml

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