Morbidity and Mortality Weekly Report: Recommendations and Reports, May 13, 2016 / Vol. 65 / No. RR-2

Details

• Alternative Title:
  Diagnosis and Management of Tickborne Rickettsial Diseases : Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichiosis, and Anaplasmosis — United States : A Practical Guide for Health Care and Public Health Professionals
• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports
• Personal Author:
  Biggs, Holly M. ; Barton Behravesh, Casey ; Bradley, Kristy K. ; Dahlgren, F. Scott ; Drexler, Naomi A. ; Dumler, J. Stephen ; Folk, Scott M. ; Kato, Cecilia Y. ; Lash, R. Ryan ; Levin, Michael L. ; Massung, Robert F. ; Nadelman, Robert B. ; Nicholson, William L. ; Paddock, Christopher D. ; Pritt, Bobbi S. ; Traeger, Marc S.
• Corporate Authors:
  National Center for Emerging and Zoonotic Infectious Diseases (U.S.)
• Description:
  Tickborne rickettsial diseases continue to cause severe illness and death in otherwise healthy adults and children, despite the availability of low-cost, effective antibacterial therapy. Recognition early in the clinical course is critical because this is the period when antibacterial therapy is most effective. Early signs and symptoms of these illnesses are nonspecific or mimic other illnesses, which can make diagnosis challenging. Previously undescribed tickborne rickettsial diseases continue to be recognized, and since 2004, three additional agents have been described as causes of human disease in the United States: Rickettsia parkeri, Ehrlichia muris-like agent, and Rickettsia species 364D. This report updates the 2006 CDC recommendations on the diagnosis and management of tickborne rickettsial diseases in the United States and includes information on the practical aspects of epidemiology, clinical assessment, treatment, laboratory diagnosis, and prevention of tickborne rickettsial diseases. The CDC Rickettsial Zoonoses Branch, in consultation with external clinical and academic specialists and public health professionals, developed this report to assist health care providers and public health professionals to 1) recognize key epidemiologic features and clinical manifestations of tickborne rickettsial diseases, 2) recognize that doxycycline is the treatment of choice for suspected tickborne rickettsial diseases in adults and children, 3) understand that early empiric antibacterial therapy can prevent severe disease and death, 4) request the appropriate confirmatory diagnostic tests and understand their usefulness and limitations, and 5) report probable and confirmed cases of tickborne rickettsial diseases to public health authorities.
  
  Suggested citation for this article: Biggs HM, Behravesh CB, Bradley KK, et al. Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis — United States. MMWR Recomm Rep 2016;65(No. RR-2):1–44. DOI: http://dx.doi.org/10.15585/mmwr.rr6502a1.
  
  rr6502.pdf
  
  PMID: 27172113
  
  
• Subjects:
  Anaplasmosis / Diagnosis Anaplasmosis / Epidemiology Anaplasmosis / Therapy Animals Anti-Bacterial Agents / Therapeutic Use Diagnosis, Differential Ehrlichiosis / Diagnosis Ehrlichiosis / Epidemiology Ehrlichiosis / Therapy Rickettsiaceae Infections / Diagnosis Rickettsiaceae Infections / Epidemiology Rickettsiaceae Infections / Therapy Rocky Mountain Spotted Fever / Diagnosis Rocky Mountain Spotted Fever / Epidemiology Rocky Mountain Spotted Fever / Therapy Tick-Borne Diseases / Diagnosis Tick-Borne Diseases / Epidemiology Tick-Borne Diseases / Therapy Ticks

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• Source:
  Morbidity and Mortality Weekly Report (MMWR): Recommendations and Reports, 2016; v. 65, no. 2
• Series:
  Recommendations and Reports: Morbidity and Mortality Weekly Report (MMWR)
• DOI:
  http://dx.doi.org/10.15585/mmwr.rr6502a1
• ISSN:
  1057-5987 (print) ; 1545-8601 (digital)
• Pubmed ID:
  27172113
• Document Type:
  Journal Issue
• Genre:
  Practice Guideline
• Place as Subject:
  United States
• Pages in Document:
  48 pdf pages
• Volume:
  65
• Issue:
  2
• Collection(s):
  Guidelines and Recommendations Morbidity and Mortality Weekly Report (MMWR)
• Main Document Checksum:
  urn:sha-512:df6b50703e1255aca7bdd92cac5b5c9fe528877e384b1a8269a0c0cb4ef0b2288408830d098ce3b1599dd1ad4b8980d1eaedda3f9938c5176cef306c1230eab8
• Download URL:
  https://stacks.cdc.gov/view/cdc/39410/cdc_39410_DS1.pdf
• File Type:
  [PDF - 5.49 MB ]