The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001–2011

Details

• Alternative Title:
  Occup Environ Med
• Personal Author:
  Weakley, Jessica ; Hall, Charles B ; Liu, Xiaoxue ; Zeig-Owens, Rachel ; Webber, Mayris P ; Schwartz, Theresa ; Prezant, David
• Description:
  Objective
  
  To assess how the effect of World Trade Center (WTC) exposure on physician-diagnosed chronic rhinosinusitis (CRS) in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011).
  
  Methods
  
  We examined temporal effects on the relation between WTC exposure and the incidence of physician diagnosed CRS in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011). Exposure was grouped by time of arrival at the WTC site as follows: (high) morning 11 September 2001 (n=1623); (moderate) afternoon 11 September 2001 or 12 September 2001 (n=7025); or (low) 13–24 September 2001 (n=1200). Piecewise exponential survival models were used to estimate incidences by exposure group, with change points in the relative incidences estimated by maximum likelihood.
  
  Results
  
  Incidences dramatically increased after 2007 due to a programmatic change that provided free medical treatment, but increases were similar in all exposure groups. For this reason, we observed no change point during the study period, meaning the relative incidence by exposure group (high vs moderate vs low) of CRS disease did not significantly change over the study period. The relative rate of developing CRS was 1.99 (95% CI=1.64 to 2.41) for high versus low exposure, and 1.52 (95% CI=1.28 to 1.80) for moderate versus low exposure during the 10-year follow-up period.
  
  Conclusions
  
  The risk of CRS in FDNY firefighters appears increased with WTC-exposure, and has not diminished by time since exposure.
  
  
• Subjects:
  Adult Air Pollution Chronic Disease Firefighters Humans Incidence Male Middle Aged Occupational Diseases Occupational Exposure Rescue Work Risk Factors September 11 Terrorist Attacks Sinusitis Surveys And Questionnaires Work Young Adult

  More +
• Source:
  Occup Environ Med. 2016; 73(4):280-283.
• Pubmed ID:
  26574577
• Pubmed Central ID:
  PMC4819651
• Document Type:
  Journal Article
• Funding:
  U01 OH010711/OH/NIOSH CDC HHS/United States
• Place as Subject:
  New York City, NY
• Volume:
  73
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:482100735177c06807398b9ee27fafff56830a96e93b49a3f42506c58721a8e1036dd41e6c5f922186a462dfd9a4a94518b1a3f378772430e69da6533a222817
• Download URL:
  https://stacks.cdc.gov/view/cdc/39191/cdc_39191_DS1.pdf
• File Type:
  [PDF - 615.72 KB ]