The Emergence of Zoonotic Onchocerca lupi Infection in the United States – A Case-Series

Cantey, Paul T.; Weeks, Jessica; Edwards, Morven; Rao, Suchitra; Ostovar, G. Amin; Dehority, Walter; Alzona, Maria; Swoboda, Sara; Christiaens, Brooke; Ballan, Wassim; Hartley, John; Terranella, Andrew; Weatherhead, Jill; Dunn, James J.; Marx, Douglas P.; Hicks, M. John; Rauch, Ronald A.; Smith, Christiana; Dishop, Megan K.; Handler, Michael H.; Dudley, Roy W. R.; Chundu, Kote; Hobohm, Dan; Feiz-Erfan, Iman; Hakes, Joseph; Berry, Ryan S.; Stepensaski, Shelly; Greenfield, Benjamin; Shroeder, Laura; Bishop, Henry; de Almeida, Marcos; Mathison, Blaine; Eberhard, Mark

i

The Emergence of Zoonotic Onchocerca lupi Infection in the United States – A Case-Series

Supporting Files

Nov 26 2015
By Cantey, Paul T. ; Weeks, Jessica ; Edwards, Morven ; ...

File Language:

English

Details

Alternative Title:

Clin Infect Dis
Personal Author:

Cantey, Paul T. ; Weeks, Jessica ; Edwards, Morven ; Rao, Suchitra ; Ostovar, G. Amin ; Dehority, Walter ; Alzona, Maria ; Swoboda, Sara ; Christiaens, Brooke ; Ballan, Wassim ; Hartley, John ; Terranella, Andrew ; Weatherhead, Jill ; Dunn, James J. ; Marx, Douglas P. ; Hicks, M. John ; Rauch, Ronald A. ; Smith, Christiana ; Dishop, Megan K. ; Handler, Michael H. ; Dudley, Roy W. R. ; Chundu, Kote ; Hobohm, Dan ; Feiz-Erfan, Iman ; Hakes, Joseph ; Berry, Ryan S. ; Stepensaski, Shelly ; Greenfield, Benjamin ; Shroeder, Laura ; Bishop, Henry ; de Almeida, Marcos ; Mathison, Blaine ; Eberhard, Mark
Description:

This case-series describes the 6 human infections with Onchocerca lupi, a parasite known to infect cats and dogs, that have been identified in the United States since 2013. Unlike cases reported outside the country, the American patients have not had subconjunctival nodules but have manifested more invasive disease (eg, spinal, orbital, and subdermal nodules). Diagnosis remains challenging in the absence of a serologic test. Treatment should be guided by what is done for Onchocerca volvulus as there are no data for O. lupi. Available evidence suggests that there may be transmission in southwestern United States, but the risk of transmission to humans is not known. Research is needed to better define the burden of disease in the United States and develop appropriately-targeted prevention strategies.
Subjects:

Adolescent Animals Cats Child Child, Preschool Communicable Diseases, Emerging Cost Of Illness Dog Diseases Dogs Female Humans Infant Male Middle Aged Onchocerca Onchocerciasis Southwestern United States Zoonoses
Source:

Clin Infect Dis. 62(6):778-783.
Pubmed ID:

26611778
Pubmed Central ID:

PMC4809994
Document Type:

Journal Article
Funding:

CC999999/Intramural CDC HHS/United States ; T32 AI055413/AI/NIAID NIH HHS/United States
Place as Subject:

United States
Volume:

62
Issue:

6
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:67caa6fad39dfd862fb80232f9e712066ad9259ed7f0b7048f77a027721d4257
Download URL:

https://stacks.cdc.gov/view/cdc/38661/cdc_38661_DS1.pdf
File Type:

[PDF - 1.47 MB ]

File Language:

English

ON THIS PAGE

Details Supporting Files

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.

As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.