Details:

Alternative Title:
Vector Borne Zoonotic Dis
Publisher's site:
http://dx.doi.org/10.1089/vbz.2015.1878
Personal Author:
Karpathy, Sandor E.; Allerdice, Michelle E.J.; Sheth, Mili; Dasch, Gregory A.; Levin, Michael L.;
Karpathy, Sandor E.; Allerdice, Michelle E.J.; Sheth, Mili; Dasch, Gregory A.; Levin, Michael L.; Less -
Description:
The Ehrlichia muris-like agent (EMLA) is a newly recognized human pathogen found in Wisconsin and Minnesota. Ecological investigations have implicated both the blacklegged tick, Ixodes scapularis, and the white-footed mouse, Peromyscus leucopus, as playing roles in the maintenance of EMLA in nature. The work presented here shows that I. scapularis is an efficient vector of EMLA in a laboratory mouse model, but that Dermacentor variabilis, another frequent human biting tick found in EMLA endemic areas, is not. Additionally, I. scapularis larvae are able to acquire EMLA through co-feeding with infected nymphs. As EMLA only persists in mouse blood for a relatively short period of time, co-feeding transmission may play an important role in the maintenance of EMLA in ticks, and subsequently may play a role in limiting the geographic distribution of this pathogen in areas where co-feeding of larvae and nymphs is less common.
Subject:
[+]
Animals
Arachnid Vectors
Disease Models, Animal
Disease Reservoirs
Ehrlichia
Ehrlichiosis
Female
Humans
Ixodes
Larva
Mice
Mice, Inbred C57BL
Nymph
Peromyscus
Rabbits
Specific Pathogen-Free Organisms
Tick Infestations
Wisconsin

Source:
Vector Borne Zoonotic Dis. 16(3):145-150.;
Pubmed ID:
26824725
Pubmed Central ID:
PMC4809518
Document Type:
Journal Article;
Funding:
CC999999/Intramural CDC HHS/United States;
Place as Subject:
Minnesota;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:80ab9416b1972813afde834cb402325cabc8585113ab7ca7662e54f17615140e
File Type:

Supporting Files

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