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Co-Feeding Transmission of the Ehrlichia muris–Like Agent to Mice (Mus musculus)
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Published Date:
Jan 29 2016
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Publisher's site:
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Source:Vector Borne Zoonotic Dis. 16(3):145-150.
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[PDF-297.50 KB]
Details:
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Alternative Title:Vector Borne Zoonotic Dis
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Personal Author:
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Description:The Ehrlichia muris-like agent (EMLA) is a newly recognized human pathogen found in Wisconsin and Minnesota. Ecological investigations have implicated both the blacklegged tick, Ixodes scapularis, and the white-footed mouse, Peromyscus leucopus, as playing roles in the maintenance of EMLA in nature. The work presented here shows that I. scapularis is an efficient vector of EMLA in a laboratory mouse model, but that Dermacentor variabilis, another frequent human biting tick found in EMLA endemic areas, is not. Additionally, I. scapularis larvae are able to acquire EMLA through co-feeding with infected nymphs. As EMLA only persists in mouse blood for a relatively short period of time, co-feeding transmission may play an important role in the maintenance of EMLA in ticks, and subsequently may play a role in limiting the geographic distribution of this pathogen in areas where co-feeding of larvae and nymphs is less common.
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Subject:
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Pubmed ID:26824725
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Pubmed Central ID:PMC4809518
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