Calculating total daily dose of opioids for safer dosage
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Calculating total daily dose of opioids for safer dosage

  • Published Date:

    3/14/16

  • Language:
    English
Filetype[PDF-2.04 MB]


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  • Description:
    Higher Dosage, Higher Risk. Higher dosages of opioids are associated with higher risk of overdose and death—even relativelylow dosages (20-50 morphine milligram equivalents (MME) per day) increase risk. Higher dosages haven’t been shown to reduce pain over the long term. One randomized trial found no differencein pain or function between a more liberal opioid dose escalation strategy (with average final dosage 52 MME) and maintenance of current dosage (average final dosage 40 MME). Learn more: ww.cdc.gov/drugoverdose/prescribing/guideline.html Fact sheet for: Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR Recomm Rep 2016;65:1–49. Date from document properties. calculating_total_daily_dose-a.pdf
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