Calculating Total Daily Dose of Opioids for Safer Dosage
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2016/03/14
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Description:Higher Dosage, Higher Risk. Higher dosages of opioids are associated with higher risk of overdose and death—even relatively low dosages (20-50 morphine milligram equivalents (MME) per day) increase risk. Higher dosages haven’t been shown to reduce pain over the long term. One randomized trial found no difference in pain or function between a more liberal opioid dose escalation strategy (with average final dosage 52 MME) and maintenance of current dosage (average final dosage 40 MME). Learn more: https://www.cdc.gov/overdose-prevention/
Fact sheet for: Dowell D, Haegerich TM, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016. MMWR Recomm Rep 2016;65:1–49.
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Pages in Document:2 pdf pages
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Main Document Checksum:urn:sha-512:1759419c62c948f7ee67444f5f38bd2267ca77ec5a6a03d656fa8309d7e31d5a23869aec0bd126e55a9a323fa84ea31345e3b4275ddfb54b8ee3e9ff6f3703be
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