A Case-Study of Implementation of Improved Strategies for Prevention of Laboratory-acquired Brucellosis

Details

• Alternative Title:
  Saf Health Work
• Personal Author:
  Castrodale, Louisa J ; Raczniak, Gregory A ; Rudolph, Karen M ; Chikoyak, Lori ; Cox, Russell S ; Franklin, Tricia L ; Traxler, Rita M ; Guerra, Marta
• Description:
  Background
  
  In 2012, the Alaska Section of Epidemiology investigated personnel potentially exposed to a Brucella suis isolate as it transited through three laboratories
  
  Methods
  
  We summarize the first implementation of the United States Centers for Disease Control and Prevention 2013 revised recommendations for monitoring such exposures: (1) risk classification; (2) antimicrobial postexposure prophylaxis; (3) serologic monitoring; and (4) symptom surveillance
  
  Results
  
  Over 30 people were assessed for exposure and subsequently monitored for development of illness No cases of laboratory-associated brucellosis occurred Changes were made to gaps in laboratory biosafety practices that had been identified in the investigation
  
  Conclusion
  
  Achieving full compliance for the precise schedule of serologic monitoring was challenging and resource intensive for the laboratory performing testing More refined exposure assessments could inform decision making for follow-up to maximize likelihood of detecting persons at risk while not overtaxing resources
  
  
• Subjects:
  Brucellosis Laboratory-Acquired Infections Laboratory-Associated Brucellosis Laboratory Biosafety Short Communication
• Source:
  Saf Health Work 2015; 6(4):353-356
• Pubmed ID:
  26929849
• Pubmed Central ID:
  PMC4682031
• Document Type:
  Journal Article
• Place as Subject:
  Alaska
• Location:
  North America
• Volume:
  6
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:cf30f47d3be1d3af9d30bb332259bc2d23be06fdd8bf0e7850a0c1fa9582bbb9
• Download URL:
  https://stacks.cdc.gov/view/cdc/38468/cdc_38468_DS1.pdf
• File Type:
  [PDF - 200.38 KB ]