A Case-Study of Implementation of Improved Strategies for Prevention of Laboratory-acquired Brucellosis

Castrodale, Louisa J; Raczniak, Gregory A; Rudolph, Karen M; Chikoyak, Lori; Cox, Russell S; Franklin, Tricia L; Traxler, Rita M; Guerra, Marta

doi:101016/jshaw201507009

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A Case-Study of Implementation of Improved Strategies for Prevention of Laboratory-acquired Brucellosis

Aug 11 2015
By Castrodale, Louisa J ; Raczniak, Gregory A ; Rudolph, Karen M ; ...
http://dxdoiorg/101016/jshaw201507009
Source: Saf Health Work 2015; 6(4):353-356

[PDF-200.38 KB]

English

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Details:

Alternative Title:

Saf Health Work
Personal Author:

Castrodale, Louisa J ; Raczniak, Gregory A ; Rudolph, Karen M ; Chikoyak, Lori ; Cox, Russell S ; ... More +

Castrodale, Louisa J ; Raczniak, Gregory A ; Rudolph, Karen M ; Chikoyak, Lori ; Cox, Russell S ; Franklin, Tricia L ; Traxler, Rita M ; Guerra, Marta Less -
Description:

Background

In 2012, the Alaska Section of Epidemiology investigated personnel potentially exposed to a Brucella suis isolate as it transited through three laboratories

Methods

We summarize the first implementation of the United States Centers for Disease Control and Prevention 2013 revised recommendations for monitoring such exposures: (1) risk classification; (2) antimicrobial postexposure prophylaxis; (3) serologic monitoring; and (4) symptom surveillance

Results

Over 30 people were assessed for exposure and subsequently monitored for development of illness No cases of laboratory-associated brucellosis occurred Changes were made to gaps in laboratory biosafety practices that had been identified in the investigation

Conclusion

Achieving full compliance for the precise schedule of serologic monitoring was challenging and resource intensive for the laboratory performing testing More refined exposure assessments could inform decision making for follow-up to maximize likelihood of detecting persons at risk while not overtaxing resources
Subjects:

[+]

Brucellosis Laboratory-Acquired Infections Laboratory-Associated Brucellosis Laboratory Biosafety Short Communication
Source:

Saf Health Work 2015; 6(4):353-356
Pubmed ID:

26929849
Pubmed Central ID:

PMC4682031
Document Type:

Journal Article
Place as Subject:

Alaska
Location:

North America
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha256:cf30f47d3be1d3af9d30bb332259bc2d23be06fdd8bf0e7850a0c1fa9582bbb9
Download URL:

https://stacks.cdc.gov/view/cdc/38468/cdc_38468_DS1.pdf
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