All data are preliminary and may change as more reports are received. Synopsis: During week 10 (March 6-12, 2016), influenza activity increased in the United States. • Viral Surveillance: The most frequently identified influenza virus type reported by public health laboratories during week 10 was influenza A, with influenza A (H1N1)pdm09 viruses predominating. The percentage of respiratory specimens testing positive for influenza in clinical laboratories increased. • Pneumonia and Influenza Mortality: The proportion of deaths attributed to pneumonia and influenza (P&I) was below their system-specific epidemic threshold in both the NCHS Mortality Surveillance System and the 122 Cities Mortality Reporting System. • Influenza-associated Pediatric Deaths: Eight influenza-associated pediatric deaths were reported. • Influenza-associated Hospitalizations: A cumulative rate for the season of 14.5 laboratory-confirmed influenza-associated hospitalizations per 100,000 population was reported. • Outpatient Illness Surveillance: The proportion of outpatient visits for influenza-like illness (ILI) was 3.7%, which is above the national baseline of 2.1%. All 10 regions reported ILI at or above region-specific baseline levels. New York City, Puerto Rico, and 14 states experienced high ILI activity; 13 states experienced moderate ILI activity; 11 states experienced low ILI activity; 12 states experienced minimal ILI activity; and the District of Columbia had insufficient data. • Geographic Spread of Influenza: The geographic spread of influenza in Puerto Rico and 40 states was reported as widespread; Guam and 10 states reported regional activity; the District of Columbia reported local activity; and the U.S. Virgin Islands did not report. External_F1610.pdf

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