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Nhumirim virus, a novel flavivirus isolated from mosquitoes from the Pantanal, Brazil
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Published Date:
Sep 25 2014
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Publisher's site:
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Source:Arch Virol. 160(1):21-27.
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Language:English
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Details:
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Alternative Title:Arch Virol
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Personal Author:
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Description:We describe the isolation of a novel flavivirus, isolated from a pool of mosquitoes identified as Culex (Culex) chidesteri collected in 2010 in the Pantanal region of west-central Brazil. The virus is herein designated Nhumirim virus (NHUV) after the name of the ranch from which the mosquito pool was collected. Flavivirus RNA was detected by real-time RT-PCR of homogenized mosquitoes and from the corresponding C6/36 culture supernatant. Based on full-genome sequencing, the virus isolate was genetically distinct from but most closely related to Barkedji virus (BJV), a newly described flavivirus from Senegal. Phylogenetic analysis demonstrated that NHUV grouped with mosquito-borne flaviviruses forming a clade with BJV. This clade may be genetically intermediate between the Culex-borne flaviviruses amplified by birds and the insect-only flaviviruses.
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Subject:
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Pubmed ID:25252815
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Pubmed Central ID:PMC4785999
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