Details:

Alternative Title:
J Acquir Immune Defic Syndr
Publisher's site:
http://dx.doi.org/10.1097/QAI.0000000000000118
Personal Author:
Ng’eno, Bernadette ; Mwangi, Ann ; Ng’ang’a, Lucy ; Kim, Andrea A. ; Waruru, Anthony ; ... More +
Ng’eno, Bernadette ; Mwangi, Ann ; Ng’ang’a, Lucy ; Kim, Andrea A. ; Waruru, Anthony ; Mukui, Irene ; Ngugi, Evelyn W. ; Rutherford, George W. ; Less -
Description:
Backgrounds In Kenya, mathematical models estimate that there are approximately 220,000 children aged less than 15 years infected with HIV. We analyzed data from the second Kenya AIDS Indicator Survey (KAIS 2012) to estimate the prevalence of HIV infection among children aged 18 months to 14 years. Methods KAIS 2012 was a nationally representative 2-stage cluster sample household survey. We studied children aged 18 months to 14 years whose parents or guardians answered questions pertaining to their children by interview. Blood specimens were collected for HIV serology and viral load measurement. Results We identified 5162 children who were eligible for the study. Blood was obtained for 3681 (71.3%) children. Among child participants, 16.4% had been tested for HIV infection in the past, and among children with parents or guardians who self-reported HIV-positive status, 52.9% had been tested for HIV infection. Twenty-eight (0.9%) children tested HIV-positive in the survey. Of these, 11 had been previously diagnosed with HIV infection before the survey. All 11 children were in HIV care and receiving cotrimoxazole; 8 were on antiretorivral therapy (ART). Among those on ART, 4 were virologically suppressed. Conclusions HIV causes a substantial burden of disease in the Kenyan pediatric population. Although most children who had been diagnosed with HIV before the survey were engaged in care and treatment, they represented less than half of HIV-infected children identified in the survey. Future efforts should focus on identifying infected children and getting them into care and on suppressive ART as early as possible.
Subject:
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Adolescent
Age Factors
AIDS Serodiagnosis
Anti-Infective Agents
Anti-Retroviral Agents
Article
Child
Child, Preschool
Cross-Sectional Studies
Female
Health Surveys
HIV Infections
Humans
Infant
Male
Prevalence
Rural Population
Trimethoprim, Sulfamethoxazole Drug Combination
Urban Population
Viral Load

Source:
J Acquir Immune Defic Syndr. 66(Suppl 1):S82-S88. ;
Pubmed ID:
24732823
Pubmed Central ID:
PMC4784690
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ; P30 MH062246/MH/NIMH NIH HHS/United States ;
CC999999/Intramural CDC HHS/United States ; P30 MH062246/MH/NIMH NIH HHS/United States ; Less -
Place as Subject:
Kenya ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:9301efccfae0dddba34ffa95d5bec79bdbe328fa71108f167aa00f447c65f35b
File Type:

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