An Occupational Reproductive Research Agenda for the Third Millennium

Details

• Journal Article:
  Environ Health Perspect
• Personal Author:
  Lawson, Christina C. ; Schnorr, Teresa M. ; Daston, George P. ; Grajewski, Barbara A. ; Marcus, Michele ; McDiarmid, Melissa A. ; Murono, Eisuke ; Perreault, Sally D. ; Schrader, Steven M. ; Shelby, Michael
• Description:
  There is a significant public health concern about the potential effects of occupational exposure to toxic substances on reproductive outcomes. Several toxicants with reported reproductive and developmental effects are still in regular commercial or therapeutic use and thus present potential exposure to workers. Examples of these include heavy metals, organic solvents, pesticides and herbicides, and sterilants, anesthetic gases, and anticancer drugs used in health care. Many other substances are suspected of producing reproductive or developmental toxicity but lack sufficient data. Progress has been limited in identifying hazards and quantifying their potencies and in separating the contribution of these hazards from other etiologic factors. Identifying the causative agents, mechanisms by which they act, and any potential target populations, present the opportunity to intervene and protect the reproductive health of workers. The pace of laboratory studies to identify hazards and to underpin the biologic plausibility of effects in humans has not matched the pace at which new chemicals are introduced into commerce. Though many research challenges exist today, recent technologic and methodologic advances have been made that allow researchers to overcome some of these obstacles. The objective of this article is to recommend future directions in occupational reproductive health research. By bridging interdisciplinary gaps, the scientific community can work together to improve health and reduce adverse outcomes.
• Subjects:
  Communication Forecasting Occupational Health Reproduction Research Design Xenobiotics
• Keywords:
  Author Keywords: Communication; Environmental Exposure; Occupational Exposure; Reproduction; Research Design; Risk Factors Toxic-effects; Reproductive-effects; Reproductive-hazards; Reproductive-system; Reproductive-system-disorders; Occupational-exposure; Environmental-exposure; Information-retrieval-systems;
• Source:
  Environ Health Perspect. 111(4):584-592.
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies ; DART - Division of Applied Research and Technology ; HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  9 pdf pages
• Volume:
  111
• Issue:
  4
• NIOSHTIC Number:
  nn:20022914
• CAS Registry Number:
  1,2-Dibromo-3-chloropropane (CAS RN 96-12-8) ; 1,2-Dibromoethane (CAS RN 106-93-4) ; Cadmium (CAS RN 7440-43-9) ; Carbon disulfide (CAS RN 75-15-0) ; Glycol monoethyl ether (CAS RN 110-80-5) ; Lead (CAS RN 7439-92-1) ; Lithium (CAS RN 7439-93-2) ; Mercury (CAS RN 7439-97-6) ; Toluene (CAS RN 108-88-3) ; Vinyl chloride (CAS RN 75-01-4)
• Federal Fiscal Year:
  2003
• Peer Reviewed:
  True
• Collection(s):
  CDC Public Access National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2ecdf27d2321771561802ec97ac793bfb2a38fe2dd8c35cc820cb4f51a2e94f02a0ce310e84bdc9a364528a0d7fefd96cddb5e033a10ed15dacf033be5a9fd0f
• Download URL:
  https://stacks.cdc.gov/view/cdc/3837/cdc_3837_DS1.pdf
• File Type:
  [PDF - 168.07 KB ]