Alternative Methods for Defining Osteoarthritis and the Impact on Estimating Prevalence in a US Population-Based Survey

Details

• Alternative Title:
  Arthritis Care Res (Hoboken)
• Personal Author:
  Cisternas, Miriam G. ; Murphy, Louise ; Sacks, Jeffrey J. ; Solomon, Daniel H. ; Pasta, David J. ; Helmick, Charles G.
• Description:
  Objective
  
  Provide a contemporary estimate of osteoarthritis (OA) by comparing accuracy and prevalence of alternative definitions of OA.
  
  Methods
  
  The Medical Expenditure Panel Survey (MEPS) household component (HC) records respondent-reported medical conditions as open-ended responses; professional coders translate these responses into ICD-9-CM codes for the medical conditions files. Using these codes and other data from the MEPS-HC medical conditions files, we constructed three case definitions of OA and assessed them against medical provider diagnoses of ICD-9-CM 715 [osteoarthrosis and allied disorders] in a MEPS subsample. The three definitions were: 1) strict = ICD-9-CM 715; 2) expanded = ICD-9-CM 715, 716 [other and unspecified arthropathies], OR 719 [other and unspecified disorders of joint]); and 3) probable = strict OR expanded + respondent-reported prior diagnosis of OA or other arthritis excluding rheumatoid arthritis (RA).
  
  Results
  
  Sensitivity and specificity of the three definitions were: strict – 34.6% and 97.5%; expanded – 73.8% and 90.5%; and probable – 62.9% and 93.5%.
  
  Conclusion
  
  The strict definition for OA (ICD-9-CM 715) excludes many individuals with OA. The probable definition of OA has the optimal combination of sensitivity and specificity relative to the two other MEPS-based definitions and yields a national annual estimate of 30.8 million adults with OA (13.4% of US adult population) for 2008 – 2011.
  
  
• Subjects:
  Adolescent Adult Aged Female Health Surveys Humans International Classification Of Diseases Male Middle Aged Osteoarthritis Prevalence Sensitivity And Specificity Young Adult

  More +
• Source:
  Arthritis Care Res (Hoboken). 68(5):574-580.
• Pubmed ID:
  26315529
• Pubmed Central ID:
  PMC4769961
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  68
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:b036b1e171e0d8459fe4a64a8b5fea3c59a1f24d24fc82e3501d2f0c656ab12f
• Download URL:
  https://stacks.cdc.gov/view/cdc/38261/cdc_38261_DS1.pdf
• File Type:
  [PDF - 279.96 KB ]