Details:

Alternative Title:
Environ Health Perspect
Personal Author:
Lynberg, M ; Nuckols, J R ; Langlois, P ; Ashley, D ; Singer, P ; ... More +
Lynberg, M ; Nuckols, J R ; Langlois, P ; Ashley, D ; Singer, P ; Mendola, P ; Wilkes, C ; Krapfl, H ; Miles, E ; Speight, V ; Lin, B ; Small, L ; Miles, A ; Bonin, M ; Zeitz, P ; Tadkod, A ; Henry, J ; Forrester, M B Less -
Description:
We conducted a field study in Corpus Christi, Texas, and Cobb County, Georgia, to evaluate exposure measures for disinfection by-products, with special emphasis on trihalomethanes (THMs). Participants were mothers living in either geographic area who had given birth to healthy infants from June 1998 through May 1999. We assessed exposure by sampling blood and water and obtaining information about water use habits and tap water characteristics. Two 10-mL whole blood samples were collected from each participant before and immediately after her shower. Levels of individual THM species (chloroform, bromodichloromethane, dibromochloromethane, and bromoform) were measured in whole blood [parts per trillion (pptr)] and in water samples (parts per billion). In the Corpus Christi water samples, brominated compounds accounted for 71% of the total THM concentration by weight; in Cobb County, chloroform accounted for 88%. Significant differences in blood THM levels were observed between study locations. For example, the median baseline blood level of bromoform was 0.3 pptr and 3.5 pptr for participants in Cobb County and Corpus Christi, respectively (p = 0.0001). Differences were most striking in blood obtained after showering. For bromoform, the median blood levels were 0.5 pptr and 17 pptr for participants in Cobb County and Corpus Christi, respectively (p = 0.0001). These results suggest that blood levels of THM species vary substantially across populations, depending on both water quality characteristics and water use activities. Such variation has important implications for epidemiologic studies of the potential health effects of disinfection by-products.
Subject:
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Activities Of Daily Living Adult Biological Markers Data Collection Disinfectants Environmental Exposure Epidemiologic Studies Female Humans Maternal Exposure Pregnancy Reproducibility Of Results Research Article Trihalomethanes Water Supply
Source:
Environ Health Perspect. 109(6):597-604.
Document Type:
Journal Article
Funding:
U50/CCU613232/PHS HHS/United States
Place as Subject:
Georgia ; Texas
Georgia ; Texas Less -
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:d7865f88936ce59488751011e2dcd32e36b83aa7e486e315334ac14cd8b388ad
Download URL:
https://stacks.cdc.gov/view/cdc/3822/cdc_3822_DS1.pdf
File Type:

Supporting Files

• 	ehp0109-000597.nxml	txt
  	license.txt	txt

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