Details:

Alternative Title:
Int J STD AIDS
Publisher's site:
http://dx.doi.org/10.1177/0956462414526860
Personal Author:
Shah, Neha S; Kim, Evelyn; de Maria Hernández Ayala, Flor; Escobar, Maria Elena Guardado; Nieto, Ana Isabel; ... More +
Shah, Neha S; Kim, Evelyn; de Maria Hernández Ayala, Flor; Escobar, Maria Elena Guardado; Nieto, Ana Isabel; Kim, Andrea A; Paz-Bailey, Gabriela; Less -
Description:
Background Resource-limited countries have limited laboratory capability and rely on syndromic management to diagnose sexually transmitted infections (STI). We aimed to estimate the sensitivity, specificity and positive predictive value (PPV) of STI syndromic management when used as a screening method within a study setting. Methods Men who have sex with men (MSM), female sex workers (FSWs) and people living with HIV/AIDS (PLWHA) participated in a behavioural surveillance study. Data were obtained on demographics, sexual behaviours, STI history and service utilisation. Biological specimens were tested for genital inflammatory infections (Neisseria gonorrhoeae [GC], Chlamydia trachomatis [CT], Mycoplasma genitalium [MG], Trichomonas vaginalis [TV]) and genital ulcerative infection (syphilis and Herpes simplex virus-2). Results There was a high prevalence of Herpes simplex virus-2 (MSM 48.1%, FSW 82.0% and PLWHA 84.4%). Most participants reported no ulcerative symptoms and the majority of men reported no inflammatory symptoms. Sensitivity and PPV were poor for inflammatory infections among PLWHA and MSM. Sensitivity for FSWs inflammatory infections was 75%. For ulcerative infections, sensitivity was poor, but specificity and PPV were high. Conclusions Reliance on self-reported symptoms may not be an effective screening strategy for these populations. STI prevention studies should focus on symptom recognition and consider routine screening and referral for high-risk populations.
Subject:
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Adolescent
Adult
AIDS
Anal Canal
Article
Blood
Chlamydia Infections
Diagnosis
El Salvador
Female
Gonorrhea
High-risk Behaviour
HIV Infections
Homosexuality, Male
Humans
Male
Middle Aged
Prevalence
Screening
Self Report
Sexual Behavior
Sexually Transmitted Diseases, Bacterial
Sex Work
Sex Workers
Socioeconomic Factors
Surveys And Questionnaires
Syndromic
Syphilis
Trichomonas Vaginitis
Urine
Young Adult

Source:
Int J STD AIDS. 25(14):984-991.;
Pubmed ID:
24616119
Pubmed Central ID:
PMC4737585
Document Type:
Journal Article;
Funding:
CC999999/Intramural CDC HHS/United States;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:079d978655df0e32730aeb031cbf1c5ec5d590f8a50922feef56883fcf135169
File Type:

Supporting Files

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