CD4 Cell Counts at HIV Diagnosis among HIV Outpatient Study Participants, 2000–2009

Details

• Alternative Title:
  AIDS Res Treat
• Personal Author:
  Buchacz, Kate ; Armon, Carl ; Palella, Frank J. ; Baker, Rose K. ; Tedaldi, Ellen ; Durham, Marcus D. ; Brooks, John T.
• Description:
  Background. It is unclear if CD4 cell counts at HIV diagnosis have improved over a 10-year period of expanded HIV testing in the USA. Methods. We studied HOPS participants diagnosed with HIV infection ≤6 months prior to entry into care during 2000-2009. We assessed the correlates of CD4 count <200 cells/mm(3) at HIV diagnosis (late HIV diagnosis) by logistic regression. Results. Of 1,203 eligible patients, 936 (78%) had a CD4 count within 3 months after HIV diagnosis. Median CD4 count at HIV diagnosis was 299 cells/mm(3) and did not significantly improve over time (P = 0.13). Comparing periods 2000-2001 versus 2008-2009, respectively, 39% and 35% of patients had a late HIV diagnosis (P = 0.34). Independent correlates of late HIV diagnosis were having an HIV risk other than being MSM, age ≥35 years at diagnosis, and being of nonwhite race/ethnicity. Conclusions. There is need for routine universal HIV testing to reduce the frequency of late HIV diagnosis and increase opportunity for patient- and potentially population-level benefits associated with early antiretroviral treatment.
• Subjects:
  Research Article
• Source:
  AIDS Res Treat. 2012; 2012.
• Document Type:
  Journal Article
• Volume:
  2012
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:c74d454c455e733bcb3e6dd396e4e0d2276c33ffb9dcba92365a1ed8e2143720
• Download URL:
  https://stacks.cdc.gov/view/cdc/3778/cdc_3778_DS1.pdf
• File Type:
  [PDF - 525.78 KB ]