Serologic Evidence of the Geographic Distribution of Bacterial Zoonotic Agents in Kenya, 2007

Omballa, Victor O.; Musyoka, Raymond N.; Vittor, Amy Y.; Wamburu, Kabura B.; Wachira, Cyrus M.; Waiboci, Lilian W.; Abudo, Mamo U.; Juma, Bonventure W.; Kim, Andrea A.; Montgomery, Joel M.; Breiman, Robert F.; Fields, Barry S.

doi:10.4269/ajtmh.15-0320

i

Serologic Evidence of the Geographic Distribution of Bacterial Zoonotic Agents in Kenya, 2007

Supporting Files Public Domain

Nov 23 2015
By Omballa, Victor O. ; Musyoka, Raymond N. ; Vittor, Amy Y. ; ...

File Language:

English

Details

Alternative Title:

Am J Trop Med Hyg
Personal Author:

Omballa, Victor O. ; Musyoka, Raymond N. ; Vittor, Amy Y. ; Wamburu, Kabura B. ; Wachira, Cyrus M. ; Waiboci, Lilian W. ; Abudo, Mamo U. ; Juma, Bonventure W. ; Kim, Andrea A. ; Montgomery, Joel M. ; Breiman, Robert F. ; Fields, Barry S.
Description:

Diseases of zoonotic origin contribute to the burden of febrile illnesses in developing countries. We evaluated serologic evidence of exposure to Bacillus anthracis, Brucella spp., spotted fever group rickettsioses (SFGR), and typhus group rickettsioses (TGR) from samples of persons aged 15-64 years collected during a nationwide human immunodeficiency virus (HIV) serosurvey conducted in 2007 in Kenya. The seropositivity observed for pathogens was B. anthracis 11.3%, Brucella spp. 3.0%, SFGR 23.3%, and TGR 0.6%. On univariate analysis, seropositivity for each pathogen was significantly associated with the following risk factors: B. anthracis with province of residence; Brucella spp. with sex, education level, and wealth; SFGR with age, education level, wealth, and province of residence; and TGR with province of residence. On multivariate analysis, seropositivity remained significantly associated with wealth and province for B. anthracis; with sex and age for Brucella spp; and with sex, education level, and province of residence for SFGR whereas TGR had no significance. High IgG seropositivity to these zoonotic pathogens (especially, B. anthracis and SFGR) suggests substantial exposure. These pathogens should be considered in the differential diagnosis of febrile illness in Kenya.
Subjects:

Adolescent Adult Animals Anthrax Antibodies, Bacterial Bacillus Anthracis Brucella Brucellosis Demography Female Humans Male Middle Aged Rickettsiaceae Rickettsiaceae Infections Risk Factors Seroepidemiologic Studies Socioeconomic Factors Young Adult Zoonoses
Source:

Am J Trop Med Hyg. 2016; 94(1):43-51.
Pubmed ID:

26598574
Pubmed Central ID:

PMC4710443
Document Type:

Journal Article
Place as Subject:

Kenya
Volume:

94
Issue:

1
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:f1610c422e403dd8d4f0b84332c85b020ad2dc638b7861554f35d9f83964c9fd
Download URL:

https://stacks.cdc.gov/view/cdc/37756/cdc_37756_DS1.pdf
File Type:

[PDF - 702.39 KB ]

File Language:

English

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