Details:

Alternative Title:
Occup Environ Med
Personal Author:
Bao, Stephen S. ; Kapellusch, Jay M. ; Garg, Arun ; Silverstein, Barbara A. ; Harris-Adamson, Carisa ; ... More +
Bao, Stephen S. ; Kapellusch, Jay M. ; Garg, Arun ; Silverstein, Barbara A. ; Harris-Adamson, Carisa ; Burt, Susan E. ; Dale, Ann Marie ; Evanoff, Bradley A. ; Gerr, Frederic E. ; Hegmann, Kurt T. ; Merlino, Linda A. ; Thiese, Matthew S. ; Rempel, David M. Less -
Description:
Background

Six research groups independently conducted prospective studies of carpal tunnel syndrome (CTS) incidence in 54 US workplaces in 10 US States. Physical exposure variables were collected by all research groups at the individual worker level. Data from these research groups were pooled to increase the exposure spectrum and statistical power.

Objective

This paper provides a detailed description of the characteristics of the pooled physical exposure variables and the source data information from the individual research studies.

Methods

Physical exposure data were inspected and prepared by each of the individual research studies according to detailed instructions provided by an exposure sub-committee of the research consortium. Descriptive analyses were performed on the pooled physical exposure dataset. Correlation analyses were performed among exposure variables estimating similar exposure aspects.

Results

At baseline, there were a total of 3010 subjects in the pooled physical exposure dataset. Overall, the pooled data meaningfully increased the spectra of most exposure variables. The increased spectra were due to the wider range in exposure data of different jobs provided by the research studies. The correlations between variables estimating similar exposure aspects showed different patterns among data provided by the research studies.

Conclusions

The increased spectra of the physical exposure variables among the data pooled likely improved the possibility of detecting potential associations between these physical exposure variables and CTS incidence. It is also recognized that methods need to be developed for general use by all researchers for standardization of physical exposure variable definition, data collection, processing and reduction.


Subjects:
[+]
Adult Carpal Tunnel Syndrome Datasets As Topic Female Hand Humans Male Middle Aged Motor Activity Movement Occupational Diseases Occupational Exposure Occupations Physical Exertion Prospective Studies Risk Factors Work Wrist
Source:
Occup Environ Med. 72(2):130-137.
Pubmed ID:
25504866
Pubmed Central ID:
PMC4725299
Document Type:
Journal Article
Funding:
5R01OH009712/OH/NIOSH CDC HHS/United States ; R01 OH009712/OH/NIOSH CDC HHS/United States
5R01OH009712/OH/NIOSH CDC HHS/United States ; R01 OH009712/OH/NIOSH CDC HHS/United States Less -
Place as Subject:
United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:e4d84d66053fc62790de2d785ccd2971bb6865ec2563fdad1ae9630e2859cb9d
Download URL:
https://stacks.cdc.gov/view/cdc/37636/cdc_37636_DS1.pdf
File Type:

Supporting Files

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