care products among Californian adults and their children

Details

• Alternative Title:
  Environ Res
• Personal Author:
  Philippat, Claire ; Bennett, Deborah ; Calafat, Antonia M. ; Picciotto, Irva Hertz
• Description:
  Introduction
  
  Certain phenols and phthalates are used in many consumer products including personal care products (PCPs).
  
  Aims
  
  We aimed to study the associations between the use of PCPs and urinary concentrations of bio-markers of select phenols and phthalates among Californian adults and their children. As an additional aim we compared phenols and phthalate metabolites concentrations measured in adults and children urine samples collected the same day.
  
  Methods
  
  Our study relied on a subsample of 90 adult–child pairs participating in the Study of Use of Products and Exposure Related Behavior (SUPERB). Each adult and child provided one to two urine samples in which we measured concentrations of selected phenols and phthalate metabolites. We computed Spearman correlation coefficients to compare concentrations measured in adults and children urine samples collected the same day. We used adjusted linear and Tobit regression models to study the associations between the use of PCPs in the past 24 h and biomarker concentrations.
  
  Results
  
  Benzophenone-3 and parabens concentrations were higher in adults compared to their children. Conversely children had higher mono-n-butyl phthalate and mono-isobutyl phthalate concentrations. No significant difference was observed for the other compounds. The total number of different PCPs used was positively associated with urinary concentrations of methyl, propyl and butyl parabens and the main metabolite of diethyl phthalate in adults. Among children, the use of a few specific products including liquid soap, hair care products and sunscreen was positively associated with urinary concentrations of some phenols or phthalate metabolites.
  
  Discussion
  
  These results strengthen the body of evidence suggesting that use of PCPs is an important source of exposure to parabens and diethyl phthalate in adults and provide data on exposure to selected phenols and phthalates through use of PCPs in children.
  
  
• Subjects:
  Adult Article California Child Child, Preschool Cosmetics Endocrine Disruptors Environmental Exposure Female Humans Limit Of Detection Male Middle Aged Parabens Personal Care Products Phenols Phthalates Phthalic Acids Temporal Variability

  More +
• Source:
  Environ Res. 140:369-376.
• Pubmed ID:
  25929801
• Pubmed Central ID:
  PMC4724203
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States ; P01-ES011269/ES/NIEHS NIH HHS/United States ; R01-ES020392/ES/NIEHS NIH HHS/United States
• Volume:
  140
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:74c2695fb4132d6316e5283482f8fc80eca1c37153e7da02b1e4ed19c1223afb
• Download URL:
  https://stacks.cdc.gov/view/cdc/37615/cdc_37615_DS1.pdf
• File Type:
  [PDF - 418.59 KB ]