Details:

Alternative Title:
Am J Ind Med
Personal Author:
Bailey, Rachel L. ; Cox-Ganser, Jean M. ; Duling, Matthew G. ; LeBouf, Ryan F. ; Martin, Stephen B. ; ... More +
Bailey, Rachel L. ; Cox-Ganser, Jean M. ; Duling, Matthew G. ; LeBouf, Ryan F. ; Martin, Stephen B. ; Bledsoe, Toni A. ; Green, Brett J. ; Kreiss, Kathleen Less -
Description:
Rationale

Obliterative bronchiolitis in former coffee workers prompted a cross-sectional study of current workers. Diacetyl and 2,3-pentanedione levels were highest in areas for flavoring and grinding/packaging unflavored coffee.

Methods

We interviewed 75 (88%) workers, measured lung function, and created exposure groups based on work history. We calculated standardized morbidity ratios (SMRs) for symptoms and spirometric abnormalities. We examined health outcomes by exposure groups.

Results

SMRs were elevated 1.6-fold for dyspnea and 2.7-fold for obstruction. The exposure group working in both coffee flavoring and grinding/packaging of unflavored coffee areas had significantly lower mean ratio of forced expiratory volume in 1 s to forced vital capacity and percent predicted mid-expiratory flow than workers without such exposure.

Conclusion

Current workers have occupational lung morbidity associated with high diacetyl and 2,3-pentanedione exposures, which were not limited to flavoring areas.


Subjects:
[+]
2,3-pentanedione Adult Airway Obstruction Article Asthma Bronchiolitis Obliterans Coffee Cross-Sectional Studies Diacetyl Dyspnea Female Flavoring Agents Flavorings Food-Processing Industry Forced Expiratory Volume Humans Lung Male Obliterative Bronchiolitis Occupational Diseases Occupational Exposure Pentanones Respiration Spirometry Vital Capacity Workplace
Source:
Am J Ind Med. 58(12):1235-1245
Pubmed ID:
26523478
Pubmed Central ID:
PMC4715657
Document Type:
Journal Article
Funding:
CC999999/Intramural CDC HHS/United States
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:9e717ff3ccd6890a7a78743a322bf5c55260877fe6ba39d61b50d4f37551783a
Download URL:
https://stacks.cdc.gov/view/cdc/37557/cdc_37557_DS1.pdf
File Type:

Supporting Files

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