Details:

Alternative Title:
Am J Ind Med
Personal Author:
Bailey, Rachel L. ; Cox-Ganser, Jean M. ; Duling, Matthew G. ; LeBouf, Ryan F. ; Martin, Stephen B. ; ... More +
Bailey, Rachel L. ; Cox-Ganser, Jean M. ; Duling, Matthew G. ; LeBouf, Ryan F. ; Martin, Stephen B. ; Bledsoe, Toni A. ; Green, Brett J. ; Kreiss, Kathleen ; Less -
Description:
Rationale Obliterative bronchiolitis in former coffee workers prompted a cross-sectional study of current workers. Diacetyl and 2,3-pentanedione levels were highest in areas for flavoring and grinding/packaging unflavored coffee. Methods We interviewed 75 (88%) workers, measured lung function, and created exposure groups based on work history. We calculated standardized morbidity ratios (SMRs) for symptoms and spirometric abnormalities. We examined health outcomes by exposure groups. Results SMRs were elevated 1.6-fold for dyspnea and 2.7-fold for obstruction. The exposure group working in both coffee flavoring and grinding/packaging of unflavored coffee areas had significantly lower mean ratio of forced expiratory volume in 1 s to forced vital capacity and percent predicted mid-expiratory flow than workers without such exposure. Conclusion Current workers have occupational lung morbidity associated with high diacetyl and 2,3-pentanedione exposures, which were not limited to flavoring areas.
Subject:
[+]
2,3-pentanedione
Adult
Airway Obstruction
Article
Asthma
Bronchiolitis Obliterans
Coffee
Cross-Sectional Studies
Diacetyl
Dyspnea
Female
Flavoring Agents
Flavorings
Food-Processing Industry
Forced Expiratory Volume
Humans
Lung
Male
Obliterative Bronchiolitis
Occupational Diseases
Occupational Exposure
Pentanones
Respiration
Spirometry
Vital Capacity
Workplace
Coffee

Source:
Am J Ind Med. 58(12):1235-1245
Pubmed ID:
26523478
Pubmed Central ID:
PMC4715657
Document Type:
Journal Article ;
Funding:
CC999999/Intramural CDC HHS/United States ;
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:9e717ff3ccd6890a7a78743a322bf5c55260877fe6ba39d61b50d4f37551783a
File Type:

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