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Intermittent Preventive Treatment in Pregnancy With Sulfadoxine–Pyrimethamine: The Controversy Continues
  • Published Date:
    Jul 05 2012
  • Source:
    Clin Infect Dis. 55(8):1103-1105.
Filetype[PDF-44.35 KB]


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  1. In vivo efficacy of sulphadoxine-pyrimethamine for the treatment of asymptomatic parasitaemia in pregnant women in Machinga District, Malawi
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    BackgroundThe effectiveness of sulphadoxine-pyrimethamine (SP) intermittent preventive treatment of malaria in pregnancy (IPTp) might be compromised by high prevalence of resistance-associated Plasmodium falciparum dihydrofolate reductase (dhfr) and ...
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  2. Effectiveness of Intermittent Preventive Treatment With Sulfadoxine-Pyrimethamine During Pregnancy on Maternal and Birth Outcomes in Machinga District, Malawi
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    BackgroundMalaria during pregnancy is associated with low birth weight and increased perinatal mortality, especially among primigravidae. Despite increasing prevalence of malarial parasite resistance to sulfadoxine-pyrimethamine (SP), SP continues to...
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    Gutman, Julie; Eckert, Erin; Mangiaterra, Viviana; Bardají, Azucena; Aponte, John J; Menéndez, Clara; Nahlen, Bernard; Slutsker, Laurence;
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  4. Placental Malaria Is Rare Among Zanzibari Pregnant Women Who Did Not Receive Intermittent Preventive Treatment in Pregnancy
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    Plotkin, Marya; Said, Khadija; Msellem, Mwinyi I.; Chase, Rachel P.; Hendler, Natalie; Khamis, Asma Ramadhan; Roman, Elaine; Kitojo, Chonge; Schwartz, Alanna C.; Gutman, Julie; McElroy, Peter D.;
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    Jun 02 2014
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    Am J Trop Med Hyg. 2014; 91(2):367-373.
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    Zanzibar has transitioned from malaria control to the pre-elimination phase, and the continued need for intermittent preventive treatment during pregnancy (IPTp) has been questioned. We conducted a prospective observational study to estimate placenta...
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  5. Missed opportunities to deliver intermittent preventive treatment for malaria to pregnant women 2003–2013: a systematic analysis of 58 household surveys in sub-Saharan Africa
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    Andrews, Kathryn G.; Lynch, Michael; Eckert, Erin; Gutman, Julie;
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    Malar J. 14.
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    BackgroundDespite the availability of effective preventive measures, including intermittent preventive treatment for malaria during pregnancy (IPTp), malaria continues to cause substantial disease burden among pregnant women in malaria-endemic areas....
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