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Intermittent Preventive Treatment in Pregnancy With Sulfadoxine–Pyrimethamine: The Controversy Continues
  • Published Date:
    Jul 05 2012
  • Source:
    Clin Infect Dis. 55(8):1103-1105.
Filetype[PDF - 44.35 KB]


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  2. Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy
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    The antifolate sulphadoxine-pyrimethamine (SP) has been used in the intermittent prevention of malaria in pregnancy (IPTp). SP is an ideal choice for IPTp, however, as resistance of Plasmodium falciparum to SP increases, data are accumulating that SP...
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    Background : Malaria during pregnancy is associated with low birth weight and increased perinatal mortality, especially among primigravidae. Despite increasing prevalence of malarial parasite resistance to sulfadoxine-pyrimethamine (SP), SP continues...
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    Tan, Kathrine R; Katalenich, Bonnie L; Mace, Kimberly E; Nambozi, Michael; Taylor, Steve M; Meshnick, Steven R; Wiegand, Ryan E; Chalwe, Victor; Filler, Scott J; Kamuliwo, Mulakwa; Craig, Allen S;
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    Jun 09 2014
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    Malar J. 2014; 13:227.
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    Background : Intermittent preventive treatment of malaria in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) decreases adverse effects of malaria during pregnancy. Zambia implemented its IPTp-SP programme in 2003. Emergence of SP-resistant Plas...
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    Malar J. 14.
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