Sociodemographic and Hispanic Acculturation Factors and Isolated Anotia/Microtia
Published Date:Jul 30 2014
Source:Birth Defects Res A Clin Mol Teratol. 100(11):852-862.
Corporate Authors:National Birth Defects Prevention Study
European Continental Ancestry Group
Health Care Costs
Pubmed Central ID:PMC4706758
Funding:CC999999/Intramural CDC HHS/United States
U01DD000494/DD/NCBDD CDC HHS/United States
It has been observed in several studies that infants with anotia/microtia are more common among Hispanics compared with other racial/ethnic groups. We examined the association between selected Hispanic ethnicity and acculturation factors and anotia/microtia in the National Birth Defects Prevention Study (NBDPS).
We examined data from mothers of 351 infants with isolated anotia/microtia and 8,435 unaffected infants from the NBDPS with an expected delivery date from 1997 to 2007. Sociodemographic, maternal, and acculturation factors (e.g. age, maternal education, household income, BMI, gestational diabetes, folic acid, smoking, alcohol intake, study center, parental birthplace and years lived in the United States, maternal language) were assessed as overall risk factors and also as risk factors among subgroups of Hispanics (US- and foreign-born) versus non-Hispanic (NH) whites.
Compared to NH whites, both US- and foreign-born Hispanic mothers demonstrated substantially higher odds of delivering infants with anotia/microtia across nearly all strata of sociodemographic and other maternal factors (adjusted odds ratios (aORs) range: 2.3–8.3). The odds of anotia/microtia was particularly elevated among Hispanic mothers who emigrated from Mexico after age five (aOR=5.67, 95% CI=3.53–9.11) or who conducted the interview in Spanish (aOR=5.72, 95% CI=3.55–9.20).
We observed that certain sociodemographic and acculturation factors are associated with higher risks of anotia/microtia among offspring of Hispanic mothers.
You May Also Like: