Sociodemographic and Hispanic Acculturation Factors and Isolated Anotia/Microtia

Details

• Alternative Title:
  Birth Defects Res A Clin Mol Teratol
• Personal Author:
  Hoyt, Adrienne T ; Canfield, Mark A ; Shaw, Gary M ; Waller, Dorothy K ; Polen, Kara ND ; Ramadhani, Tunu ; Anderka, Marlene T ; Scheuerle, Angela E
• Corporate Authors:
  National Birth Defects Prevention Study
• Description:
  BACKGROUND
  
  It has been observed in several studies that infants with anotia/microtia are more common among Hispanics compared with other racial/ethnic groups. We examined the association between selected Hispanic ethnicity and acculturation factors and anotia/microtia in the National Birth Defects Prevention Study (NBDPS).
  
  METHODS
  
  We examined data from mothers of 351 infants with isolated anotia/microtia and 8,435 unaffected infants from the NBDPS with an expected delivery date from 1997 to 2007. Sociodemographic, maternal, and acculturation factors (e.g. age, maternal education, household income, BMI, gestational diabetes, folic acid, smoking, alcohol intake, study center, parental birthplace and years lived in the United States, maternal language) were assessed as overall risk factors and also as risk factors among subgroups of Hispanics (US- and foreign-born) versus non-Hispanic (NH) whites.
  
  RESULTS
  
  Compared to NH whites, both US- and foreign-born Hispanic mothers demonstrated substantially higher odds of delivering infants with anotia/microtia across nearly all strata of sociodemographic and other maternal factors (adjusted odds ratios (aORs) range: 2.3–8.3). The odds of anotia/microtia was particularly elevated among Hispanic mothers who emigrated from Mexico after age five (aOR=5.67, 95% CI=3.53–9.11) or who conducted the interview in Spanish (aOR=5.72, 95% CI=3.55–9.20).
  
  CONCLUSIONS
  
  We observed that certain sociodemographic and acculturation factors are associated with higher risks of anotia/microtia among offspring of Hispanic mothers.
  
  
• Subjects:
  Acculturation Adult Age Factors Alcohol Drinking Congenital Microtia Ear Auricle Educational Status Female Folic Acid Health Care Costs Hispanic Or Latino Humans Infant Male Mothers Odds Ratio Prevalence Risk Social Class White People

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• Source:
  Birth Defects Res A Clin Mol Teratol. 100(11):852-862.
• Pubmed ID:
  25074828
• Pubmed Central ID:
  PMC4706758
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States ; U01DD000494/DD/NCBDD CDC HHS/United States
• Place as Subject:
  United States
• Volume:
  100
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:127ae197a79b48b430c3afebce6f6d95adc91e4333fc60045189db7518bffc0e
• Download URL:
  https://stacks.cdc.gov/view/cdc/37384/cdc_37384_DS1.pdf
• File Type:
  [PDF - 380.95 KB ]