Prevalence of Adverse Pregnancy Outcomes, by Maternal Diabetes Status at First and Second Deliveries, Massachusetts, 1998–2007

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Kim, Shin Y. ; Kotelchuck, Milton ; Wilson, Hoyt G. ; Diop, Hafsatou ; Shapiro-Mendoza, Carrie K. ; England, Lucinda J.
• Description:
  Introduction ; Understanding patterns of diabetes prevalence and diabetes-related complications across pregnancies could inform chronic disease prevention efforts. We examined adverse birth outcomes by diabetes status among women with sequential, live singleton deliveries. ; Methods ; We used data from the 1998–2007 Massachusetts Pregnancy to Early Life Longitudinal Data System, a population-based cohort of deliveries. We restricted the sample to sets of parity 1 and 2 deliveries. We created 8 diabetes categories using gestational diabetes mellitus (GDM) and chronic diabetes mellitus (CDM) status for the 2 deliveries. Adverse outcomes included large for gestational age (LGA), macrosomia, preterm birth, and cesarean delivery. We computed prevalence estimates for each outcome by diabetes status. ; Results ; We identified 133,633 women with both parity 1 and 2 deliveries. Compared with women who had no diabetes in either pregnancy, women with GDM or CDM during any pregnancy had increased risk for adverse birth outcomes; the prevalence of adverse outcomes was higher in parity 1 deliveries among women with no diabetes in parity 1 and GDM in parity 2 (for LGA 8.5% vs 15.1%, macrosomia 9.7% vs. 14.9%, cesarean delivery 24.7% vs 31.3%, and preterm birth 7.7% vs 12.9%); and higher in parity 2 deliveries among those with GDM in parity 1 and no diabetes in parity 2 (for LGA 12.3% vs 18.2%, macrosomia 12.3% vs 17.2%, and cesarean delivery 27.0% vs 37.9%). ; Conclusions ; Women with GDM during one of 2 sequential pregnancies had elevated risk for adverse outcomes in the unaffected pregnancy, whether the diabetes-affected pregnancy preceded or followed it.
• Subjects:
  • Original Research
  • Adult
  • Birth Weight
  • Cesarean Section
  • Diabetes, Gestational
  • Female
  • Fetal Macrosomia
  • Humans
  • Parity*
  • Pregnancy
  More +
• Source:
  Prev Chronic Dis. 12.
• DOI:
  http://dx.doi.org/10.5888/pcd12.150362
• ISSN:
  1545-1151
• Pubmed ID:
  26652218
• Pubmed Central ID:
  PMC4676277
• Document Type:
  Journal Article
• Place as Subject:
  Massachusetts
• Location:
  North America
• Volume:
  12
• Download URL:
  https://stacks.cdc.gov/view/cdc/37185/cdc_37185_DS1.pdf
• File Type:
  [PDF - 345.71 KB]
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:b306585ddd44c6fd0ae426480909a230524071c6e6c2a40fe25021a271ec9f7a69c16dfc30d2389a25f270ccdc3e338a05b3a7e8541ae593bb6197f4dd6d6145