Isocyanates and Work-Related Asthma: Findings From California, Massachusetts, Michigan, and New Jersey, 1993–2008
Published Date:Sep 9 2015
Source:Am J Ind Med. 58(11):1138-1149.
Air Pollutants, Occupational
Centers For Disease Control And Prevention (U.S.)
National Institute For Occupational Safety And Health (U.S.)
Occupational Disease Prevention
Occupational Health Surveillance
Pubmed Central ID:PMC4697263
Funding:U60 OH 008485/OH/NIOSH CDC HHS/United States
U60 OH 008466/OH/NIOSH CDC HHS/United States
CC999999/Intramural CDC HHS/United States
U60 OH 008490/OH/NIOSH CDC HHS/United States
U60 OH 008468/OH/NIOSH CDC HHS/United States
Isocyanates remain a leading cause of work-related asthma (WRA). Methods Two independent data systems were analyzed for the period 1993–2008: (1) State-based WRA case surveillance data on persons with isocyanate-induced WRA from four states, and (2) Occupational Safety and Health Administration (OSHA) Integrated Management Information System (IMIS) isocyanate air sampling results.
We identified 368 cases of isocyanate-induced WRA from 32 industries and 678 OSHA isocyanate air samples with detectable levels from 31 industries. Seventeen industries were unique to one or the other dataset.
Isocyanate-induced WRA continues to occur in a wide variety of industries. Two data systems uncovered industries with isocyanate exposures and/or illness. Improved control measures and standards, including medical surveillance, are needed. More emphasis is needed on task-specific guidance, spill clean-up procedures, skin and respiratory protection, and targeted medical monitoring to mitigate the hazards of isocyanate use.
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