Association of DASH Diet With Cardiovascular Risk Factors in Youth With Diabetes Mellitus The SEARCH for Diabetes in Youth Study

Details

• Alternative Title:
  Circulation
• Personal Author:
  Liese, Angela D. ; Bortsov, Andrey ; Günther, Anke L.B. ; Dabelea, Dana ; Reynolds, Kristi ; Standiford, Debra A. ; Liu, Lenna ; Williams, Desmond E. ; Mayer-Davis, Elizabeth J. ; D'Agostino, Ralph B. ; Bell, Ronny ; Marcovina, Santica
• Description:
  Background
  
  We have shown that adherence to the Dietary Approaches to Stop Hypertension (DASH) diet is related to blood pressure in youth with type 1 and type 2 diabetes mellitus. We explored the impact of the DASH diet on other cardiovascular disease risk factors.
  
  Methods and Results
  
  Between 2001 and 2005, data on total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, low-density lipoprotein particle density, apolipoprotein B, body mass index, waist circumference, and adipocytokines were ascertained in 2130 youth aged 10 to 22 years with physician-diagnosed diabetes mellitus. Dietary intake was assessed by food frequency questionnaire, categorized into the DASH food groups, and assigned an adherence score. Among youth with type 1 diabetes mellitus, higher adherence to the DASH diet was significantly and inversely associated with low-density lipoprotein/high-density lipoprotein ratio and A1c in multivariable-adjusted models. Youth in the highest adherence tertile had an estimated 0.07 lower low-density lipoprotein/high-density lipoprotein ratio and 0.2 lower A1c levels than those in the lowest tertile adjusted for confounders. No significant associations were observed with triglycerides, low-density lipoprotein particle density, adipocytokines, apolipoprotein B, body mass index Z score, or waist circumference. Among youth with type 2 diabetes mellitus, associations were observed with low-density lipoprotein particle density and body mass index Z score.
  
  Conclusions
  
  The DASH dietary pattern may be beneficial in the prevention and management of cardiovascular disease risk in youth with diabetes mellitus.
  
  
• Subjects:
  Adolescent Age Factors Article Child Cholesterol, HDL Cholesterol, LDL Diabetes Mellitus Diabetes Mellitus, Type 1 Diabetes Mellitus, Type 2 Diet, Sodium-Restricted Female Humans Hypertension Lipids Lipoproteins Male Nutrition Risk Factors Young Adult Youth

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• Source:
  Circulation. 123(13):1410-1417.
• Pubmed ID:
  21422385
• Pubmed Central ID:
  PMC4669039
• Document Type:
  Journal Article
• Funding:
  M01RR00037/RR/NCRR NIH HHS/United States ; U01 DP000247/DP/NCCDPHP CDC HHS/United States ; U01 DP000245/DP/NCCDPHP CDC HHS/United States ; M01 RR000069/RR/NCRR NIH HHS/United States ; M01 RR01070/RR/NCRR NIH HHS/United States ; U01 DP000248/DP/NCCDPHP CDC HHS/United States ; M01 RR000037/RR/NCRR NIH HHS/United States ; U01 DP000244/DP/NCCDPHP CDC HHS/United States ; M01 RR001271/RR/NCRR NIH HHS/United States ; 1UL1RR026314-01/RR/NCRR NIH HHS/United States ; UL1 RR025014/RR/NCRR NIH HHS/United States ; M01 RR00069/RR/NCRR NIH HHS/United States ; M01 RR001070/RR/NCRR NIH HHS/United States ; U01 DP000250/DP/NCCDPHP CDC HHS/United States ; U01 DP000246/DP/NCCDPHP CDC HHS/United States ; U01 DP000254/DP/NCCDPHP CDC HHS/United States ; UL1 RR026314/RR/NCRR NIH HHS/United States ; M01RR001271/RR/NCRR NIH HHS/United States
• Volume:
  123
• Issue:
  13
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:0d2f6f8a141330f30988009e77e7272a90095bbb4a161249d63eefbf41df8b8a
• Download URL:
  https://stacks.cdc.gov/view/cdc/36750/cdc_36750_DS1.pdf
• File Type:
  [PDF - 440.89 KB ]