Dose-Response Associations Between Number and Frequency of Substance Use and High-Risk Sexual Behaviors Among HIV-Negative Substance-Using Men Who Have Sex With Men (SUMSM) in San Francisco

Santos, Glenn-Milo; Coffin, Phillip O.; Das, Moupali; Matheson, Tim; DeMicco, Erin; Raiford, Jerris L.; Vittinghoff, Eric; Dilley, James W.; Colfax, Grant; Herbst, Jeffrey H.

doi:10.1097/QAI.0b013e318293f10b

i

Dose-Response Associations Between Number and Frequency of Substance Use and High-Risk Sexual Behaviors Among HIV-Negative Substance-Using Men Who Have Sex With Men (SUMSM) in San Francisco

Supporting Files

Aug 1 2013
By Santos, Glenn-Milo ; Coffin, Phillip O. ; Das, Moupali ; ...

Details

Alternative Title:

J Acquir Immune Defic Syndr
Personal Author:

Santos, Glenn-Milo ; Coffin, Phillip O. ; Das, Moupali ; Matheson, Tim ; DeMicco, Erin ; Raiford, Jerris L. ; Vittinghoff, Eric ; Dilley, James W. ; Colfax, Grant ; Herbst, Jeffrey H.
Description:

We evaluated the relationship between frequency and number of substances used and HIV risk [ie, serodiscordant unprotected anal intercourse (SDUAI)] among 3173 HIV-negative substance-using MSM. Compared with nonusers, the adjusted odds ratio (AOR) for SDUAI among episodic and at least weekly users, respectively, was 3.31 [95% confidence interval (CI), 2.55 to 4.28] and 5.46 (95% CI, 3.80 to 7.84) for methamphetamine, 1.86 (95% CI, 1.51 to 2.29) and 3.13 (95% CI, 2.12 to 4.63) for cocaine, and 2.08 (95% CI, 1.68 to 2.56) and 2.54 (95% CI, 1.85 to 3.48) for poppers. Heavy alcohol drinkers reported more SDUAI than moderate drinkers [AOR, 1.90 (95% CI, 1.43 to 2.51)]. Compared with nonusers, AORs for using 1, 2, and ≥3 substances were 16.81 (95% CI, 12.25 to 23.08), 27.31 (95% CI, 18.93 to 39.39), and 46.38 (95% CI, 30.65 to 70.19), respectively. High-risk sexual behaviors were strongly associated with frequency and number of substances used.
Subjects:

Adult Alcohol Drinking Alcohol Use Article Cocaine Confidence Intervals Cross-Sectional Studies HIV HIV Seronegativity Homosexuality, Male Humans Male Marijuana Smoking Methamphetamine MSM Nitrates Odds Ratio Pentanols Poppers Risk-Taking San Francisco Sexual Risk Behaviors Street Drugs Substance-Related Disorders Substance Use Unsafe Sex Young Adult
Source:

J Acquir Immune Defic Syndr. 63(4):540-544.
Pubmed ID:

23572012
Pubmed Central ID:

PMC4671496
Document Type:

Journal Article
Funding:

UR6PS000684/PS/NCHHSTP CDC HHS/United States
Volume:

63
Issue:

4
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:d7b193c38e228b0907902e97ec6107fc2f57e254b5cf1ac4fb60454349fd6c70
Download URL:

https://stacks.cdc.gov/view/cdc/36579/cdc_36579_DS1.pdf
File Type:

[PDF - 458.62 KB ]

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