Increased Decline in Pulmonary Function Among Employees in Norwegian Smelters Reporting Work-Related Asthma-Like Symptoms

Details

• Alternative Title:
  J Occup Environ Med
• Personal Author:
  Søyseth, Vidar ; Johnsen, Helle Laier ; Henneberger, Paul K. ; Kongerud, Johny
• Description:
  Objective
  
  To investigate associations between work-related asthma-like symptoms (WASTH) and annual pulmonary function decline among employees of 18 Norwegian smelters.
  
  Methods
  
  A 5-year longitudinal study in which WASTH was defined as a combination of dyspnea and wheezing that improved on rest days and vacation.
  
  Results
  
  A total of 12,966 spirometry examinations were performed in 3084 employees. Crude annual decline in forced expiratory volume in 1 second (FEV1) (dFEV1) was 32.9 mL/yr (95% confidence interval, 30.5 to 35.3), and crude annual decline in forced vital capacity (FVC) (dFVC) was 40.9 mL/yr (37.8 to 43.9). After adjustment for relevant covariates, employees reporting WASTH showed higher dFEV1 by 16.0 m:/yr (3.4 to 28.6) and higher dFVC by 20.5 mL/yr (6.0 to 35.0) compared with employees not reporting WASTH.
  
  Conclusion
  
  Work-related asthma-like symptom was associated with greater annual declines in FEV1 and FVC, indicating a restrictive pattern.
  
  
• Subjects:
  Article
• Source:
  J Occup Environ Med. 57(9):1004-1008.
• Pubmed ID:
  26340289
• Pubmed Central ID:
  PMC4664453
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHS/United States
• Volume:
  57
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:94afa4c92c8d9d20d4522ecb555eec2286f7c4a5598666e12361e48f0816f93d
• Download URL:
  https://stacks.cdc.gov/view/cdc/36245/cdc_36245_DS1.pdf
• File Type:
  [PDF - 592.59 KB ]