Enhancing vaccine safety capacity globally: a lifecycle perspective

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Chen, Robert T. ; Shimabukuro, Tom T. ; Martin, David B. ; Zuber, Patrick L.F. ; Weibel, Daniel M. ; Sturkenboom, Miriam
• Description:
  Major vaccine safety controversies have arisen in several countries beginning in the last decades of 20th century. Such periodic vaccine safety controversies are unlikely to go away in the near future as more national immunization programs mature with near elimination of target vaccine-preventable diseases that result in relative greater prominence of adverse events following immunizations, both true reactions and temporally coincidental events. There are several ways in which vaccine safety capacity can be improved to potentially mitigate the impact of future vaccine safety controversies. This paper aims to take a "lifecycle" approach, examining some potential pre- and post-licensure opportunities to improve vaccine safety, in both developed (specifically U.S. and Europe) and low- and middle-income countries.
• Keywords:
  Adverse Drug Reaction Reporting Systems AEFI Capacity Building Drug Approval Europe Humans Immunization Programs Licensure LMICs Product Surveillance, Postmarketing Safety Sustainability United States Vaccination Vaccines Vaccine Safety

  More +
• Source:
  Vaccine. 33(0 4):D46-D54
• Pubmed ID:
  26433922
• Pubmed Central ID:
  PMC4663114
• Document Type:
  Journal Article
• Funding:
  001/WHO_/World Health OrganizationInternational/ ; CC999999/Intramural CDC HHSUnited States/
• Volume:
  33
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:a7d312ebf1916d5bc78a671015c246907e3216a6ca623862348c799f99b3d247
• Download URL:
  https://stacks.cdc.gov/view/cdc/36237/cdc_36237_DS1.pdf
• File Type:
  [PDF - 313.32 KB ]