NIOSH Skin Notation (SK) Profile: Captafol [CAS No. 2425-06-1]

Details

• Alternative Title:
  NIOSH skin notation profile
• Journal Article:
  National Institute for Occupational Safety and Health
• Personal Author:
  Hudson, Naomi L. ; Dotson, G. Scott
• Description:
  This skin notation profile presents (1) a brief summary of epidemiological and toxicological data associated with skin contact with captafol and (2) the rationale behind the hazardspecific skin notation (SK) assignment for captafol. The SK assignment is based on the scientific rationale and logic outlined in the Current Intelligence Bulletin (CIB) 61: A Strategy for Assigning New NIOSH Skin Notations [NIOSH 2009]. The summarized information and health hazard assessment are limited to an evaluation of the potential health effects of dermal exposure to captafol. A literature search was conducted through August 2014 to identify information on captafol, including but not limited to data relating to its toxicokinetics, acute toxicity, repeated-dose systemic toxicity, carcinogenicity, biological system/function-specific effects (including reproductive and developmental effects and immunotoxicity), irritation, and sensitization. Information was considered from studies of humans, animals, or appropriate modeling systems that are relevant to assessing the effects of dermal exposure to captafol. [Description provided by NIOSH]
• Subjects:
  Animals Case Reports Dermatitis Epidemiology Fungi Fungicide, Industrial Hazardous Substances Hypersensitivity Occupational Health Risk Assessment Risk Factors Safety Skin Skin Diseases Toxicology

  More +
• Keywords:
  Skin-exposure; Skin; Exposure-levels; Risk-factors; Epidemiology; Toxicology; Health-hazards; Toxic-effects; Humans; Animal-studies; Animals; Biological-systems; Dose-response; Skin-sensitivity; Skin-irritants; Allergic-reactions; Allergies; Skin-disorders; Epidemiology; Case-studies; Dermatitis; Contact-dermatitis; Fungicides; Dermal-exposure
• Source:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 2015-193, 2015 Jul; :1-8
• Series:
  NIOSH Numbered Publications
• Subseries:
  Skin Notation Profile
• DOI:
  https://doi.org/10.26616/NIOSHPUB2015193
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Periodical
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  EID - Education and Information Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  24 pdf pages
• NIOSHTIC Number:
  nn:20046775
• NTIS Accession Number:
  PB2016-100643
• CAS Registry Number:
  Captafol (CAS RN 2425-06-1)
• Federal Fiscal Year:
  2015
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a4d9000d6b192cc10cd4ba698b8257adeda794f6d633105447fdd64bc245ce0bb9eb80512a447c68cb3df63fdbcdfd0ba470852ea9981a7dd6b80855350705d4
• Download URL:
  https://stacks.cdc.gov/view/cdc/36087/cdc_36087_DS1.pdf
• File Type:
  [PDF - 329.95 KB ]