Monitoring vaccine safety during an influenza pandemic.

Details

• Alternative Title:
  Yale J Biol Med
• Personal Author:
  Iskander, John K. ; Haber, Penina ; Herrera, Guillermo
• Description:
  In the event that a vaccine is available during an influenza pandemic, vaccine safety monitoring will occur as part of comprehensive public health surveillance of the vaccination campaign. Though inactivated influenza vaccines have been widely used in the United States and much is known about their safety profile, attention will need to be paid to both common self-limited adverse reactions and rarer, more serious events that may or may not be causally related to vaccination. The primary surveillance systems used to generate and test hypotheses about vaccine safety concerns are the Vaccine Adverse Event Reporting System (VAERS) and the Vaccine Safety Datalink (VSD), respectively. Examples of recent use of these systems to investigate influenza vaccine safety and enhancements planned for use during a pandemic are presented. Ethical issues that will need to be addressed as part of an overall vaccine safety response include risk communication and injury compensation. Advance planning and the use of available technologic solutions are needed to respond to the scientific and logistic challenges involved in safely implementing mass vaccination during a pandemic.
• Subjects:
  Adverse Drug Reaction Reporting Systems Disaster Planning Disease Notification Disease Outbreaks Drug-Related Side Effects And Adverse Reactions Humans Influenza, Human Influenza Vaccines Mandatory Reporting Population Surveillance
• Source:
  Yale J Biol Med. 78(5):265-275.
• Document Type:
  Journal Article
• Place as Subject:
  United States
• Volume:
  78
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:81445a845b248b27a3a274264d06f9479e5e11a3d3b026b19f774f77708f639bc90b3134bf6d197ffa89a5b815f374f7a7efe33088b57a2bd524f1e4acc33a5d
• Download URL:
  https://stacks.cdc.gov/view/cdc/3598/cdc_3598_DS1.pdf
• File Type:
  [PDF - 221.83 KB ]